Typical brain networks consist of many peripheral regions and a few highly central ones, i.e., hubs, playing key functional roles in cerebral inter-regional interactions. Studies have shown that networks, obtained from the analysis of specific frequency components of brain activity, present peculiar architectures with unique profiles of region centrality. However, the identification of hubs in ...

Abstract This paper proposes a multi-objective mixed-integer linear programming to model cold chain with complementary operations on hierarchical hub network. Central hubs are linked each other in the first level of network and star lower-level hubs. As for case study, different levels provide various refreshing or freezing keep perishable goods fresh along Disruption is formulated by considera...

Duplications of genes encoding highly connected and essential proteins are selected against in several species but not in human, where duplicated genes encode highly connected proteins. To understand when and how gene duplicability changed in evolution, we compare gene and network properties in four species (Escherichia coli, yeast, fly, and human) that are representative of the increase in evo...

With increasing security threats in internet environments, we may therefore want to establish a secure mechanism for data transmissions on each network. This paper presents a mechanism for establishing secure switching local area networks (LANs) by using intelligent switching hubs. Then we can achieve secure internet environments by means of the proposed switching LANs and firewalls. The propos...

The human brain is a complex network of interlinked regions. Recent studies have demonstrated the existence of a number of highly connected and highly central neocortical hub regions, regions that play a key role in global information integration between different parts of the network. The potential functional importance of these "brain hubs" is underscored by recent studies showing that distur...

Marion Koopmans tells Fiona Fleck why the world needs a publicly-funded network of hubs in all regions with local experts able to respond to infectious disease threats as they emerge.

In this article we analyze the global flow of migrants from 206 source countries to 145 destination countries (2006-2010) and focus on the differences in the migration network pattern between destination and source counters as represented by its degree and weight distribution. Degree represents the connectivity of a country to the global migration network, and plays an important role in definin...

It has been shown that the central metabolic network of Escherichia coli is of the small-world type. In this paper, we present that the metabolic network of glycolysis and TCA cycle as a part of the E. coli metabolism is also a small-world network. We found that the hubs of the studied network are consistent with those found in the complete metabolic network. The evolutionary meaning of this fi...

We have generated a protein-protein interaction network in Bacillus subtilis focused on several essential cellular processes such as cell division, cell responses to various stresses, the bacterial cytoskeleton, DNA replication and chromosome maintenance by careful application of the yeast two-hybrid approach. This network, composed of 793 interactions linking 287 proteins with an average conne...

We define and study two new kinds of “effective resistances” based on hubs-biased – hubs-repelling hubs-attracting models navigating a graph/network. prove that these effective resistances are squared Euclidean distances between the vertices graph. They can be expressed in terms Moore–Penrose pseudoinverse Laplacian matrices analogous Kirchhoff indices graph resistance distances. several result...