PROBLEMS/OBJECTIVES Malignant peripheral nerve sheath tumours are uncommon soft tissue tumours originating from Schwann cells or nerve sheath cells. Malignant epithelioid schwannoma is an aggressive variant of malignant peripheral nerve sheath tumour, and unfortunately is related with a high rate of recurrence and poor prognosis. METHODOLOGY In this study we present a rare case of malignant e...

Multiple sclerosis is a disease of the brain and spinal cord caused by demyelination (loss of the insulating sheath) of nerve fibres, believed to be caused by some substance dissolving or breaking-up fatty tissue of the nerve-sheath. The condition is progressive but varies in intensity, with remission of symptoms and relapse commonly reported. Common symptoms include fatigue, balance problems, ...

We present an extremely unusual case of an extratemporal facial nerve malignant peripheral nerve sheath tumor (MPNST) arising from preexistent intratemporal neurofibroma, illustrating a difficulty in discriminating between perineural spread of the MPNST and the preexistent intratemporal neurofibroma on preoperative radiographic images. The most interesting point was that preoperative CT scan an...

Background: Nerve recovery after a complex trauma is affected by many factors and poorly vascularized bed often the cause of failure perineural scar. Many techniques have been devised to avoid this problem possibility transfer nerve with surrounding viable sliding tissue could help in purpose; Methods: We performed an anatomic study on 8 injected specimens investigate raise medial sural artery ...

Schwannomas are benign nerve sheath tumors composed of Schwann cells, which normally produce the insulating myelin sheath covering peripheral, cranial and autonomic nerves. Twenty-five to forty-five percent of all schwannomas occur in the head and neck region, but location of such tumors in the larynx is rarely observed. The present report is aimed at describing a clinical case of laryngeal sch...

A 15-year-old boy with neurofibromatosis type 1 (NF1) was referred to us for central venous catheter insertion, and on ultrasound of the neck, he was found to have extensive involvement of the brachial plexus due to the nerve sheath tumour. Multiple hypoechogenic lesions resembling the internal jugular vein and internal carotid artery were visualised and could be differentiated from the vessels...

Raised intracranial pressure is a complication not just of traumatic brain injury and other acute cerebral insults, but also of a number of general medical conditions. Bedside diagnosis can be difficult; early clinical signs may be misinterpreted, and reliance on cross-sectional imaging studies may further delay diagnosis. Ultrasound is a readily available imaging modality in most critical care...

BACKGROUND The objective of this study was to evaluate the effect on outcomes of intraoperative recombinant human interleukin-2 injection after surgical resection of peripheral nerve sheath tumours. In this double-blind trial, 40 patients due to undergo surgical excision (<5 mm margins) of presumed peripheral nerve sheath tumours were randomized to receive intraoperative injection of interleuki...