The implantation of any foreign material into the body leads to development an inflammatory and fibrotic process—the reaction (FBR). Upon a tissue, cells immune system become attracted attempt degrade it. If this degradation fails, fibroblasts envelop form physical barrier isolate it from rest body. Long-term medical devices faces great challenge presented by FBR, as cellular response disrupts ...

to evaluate the effects of local administration of the fetal brain extract (fbe) on the crushed peripheral nerve, 15 male wistar rats were used. the right sciatic nerve of 10 rats was locally underwent the tense compression for 30 seconds and then randomly divided into experimental and control (sham) groups. the remained rats were considered as intact animals. treatment was commenced weekly, by...

introduction: arteriovenous fistulas (avf) make chronic hemodialysis easy, but the complications are unpredictable. ischemic neuropathy due to arterial insufficiency is one of the most important complications of avf. this study was designed to evaluate ischemic neuropathy using electro diagnostic method in the extremity carrying fistula. methods: in this cross-sectional study, 37 hemodialysis p...

introduction: the brachial plexus is responsible for the innervation to the upper limb and some parts of the thorax. variations in the branching of the brachial plexus are common and have been reported in 65.3% of the population. the variations (atypical communication) of brachial plexus have significant clinical and surgical importance. methods: in this study 10 upper limbs which belonged to 5...

footdrop is a relatively common deficit among the neurological disorders, which has different causes with various levels of involvement in neuromuscular system, including central nervous system (brain cortex, spinal cord), fifth lumbar root, peripheral nerves and muscles. peroneal nerve injury at the fibular head has been reported to the most common cause of foot drop, which can be due to infar...

conclusions our anesthesia method was sciatic and femoral nerve block under double ultrasonic and nerve stimulator guidance. case presentation in this case report, we present a patient who had tibia and fibula fractures and a symptomatic severe critical aortic stenosis which was diagnosed during a preoperative visit. the patient had exertional dyspnea, palpitations and fainting history, but he ...

excessive scarring; paralleling the process in tendon reconstruction of the hand. inspired by the advantages of the two-stage technique in tendon grafting and with encouraging preliminary results, we aimed to investigate the two-stage nerve grafting technique as an alternative method of secondary nerve repair. methods:  thirty female rats (~200 g) were randomly distributed into two groups (n=15...

The relationship between the anatomy and neurochemistry of neurons in the ventral medulla oblongata in regions that is responsible for cardiovascular, airways, and respiratory regulation was investigated. Microinjections of excitant amino acid (glutamate, 100 nl, 100 mM) were made throughout the ventral medulla in anesthetized rats. Arterial blood pressure, sympathetic nerve activity and phreni...

Inflammation is portion of the body's immune response and it is basically a host protective response to tissue ischemia, injury, autoimmune responses or infectious agents. Although the information presented so far points to a detrimental role for inflammation in central nervous system (CNS) disease, it may also be useful. CNS demonstrates characteristic of inflammation, and in response to damag...