Renal diseases have emerged as a critical health problem that has significant impact on human health. One of the most prevalent kidney issues is nephrotoxicity, which happens when body exposed to medicine or toxin. As result kidneys being damaged by major factors such ischemia, hypoxia, antibiotics, chemotherapy, and NSAIDS, condition known acute renal failure can develop. Due high mortality ra...

Adenine-induced model of chronic kidney disease (CKD) is a widely used model especially in studies testing novel nephroprotective agents. We investigated the effects of adenine-induced CKD in rats on the activities of some xenobiotic metabolizing enzymes in liver and kidneys, and on some in vivo indicators of drug metabolism (viz pentobarbitone sleeping time, and plasma concentration of theophy...

Helicanthes elasticus (Desr.) Danser is a member of family Loranthaceae which found widely growing on mango trees in southern India. Alkaloids, carbohydrate, steroids, tannins, saponins, phenols, flavonoids and triterpenoids are mainly believed to be responsible for its wide therapeutic actions. It known possess medicinal activities such as antimicrobial activity, immunomodulatory hepatoprotect...