Efficient and low-cost surface-enhanced Raman scattering (SERS) substrates based on Au coated zinc oxide layers for the detection of neopterin were prepared. These substrates showed high sensitivity to p-mercaptobenzoic acid (p-MBA) at a low concentration of 10(-9) M and an enhancement factor of over 10(7) was achieved. The uniform density of SERS-active "hot-spots" on a Si/ZnO/Au surface resul...

This study aims to determine serum neopterin, procalcitonin, total sialic acid (TSA), paraoxonase-1 (PON1), and some haematological indices in calves with aspiration pneumonia (ASP). The patient group consisted of 30 the Simmental breed, 0–28 days old, diagnosed ASP upon clinical examination, anamnesis, auscultation radiographic results. control 10 healthy calves, otherwise same characteristics...

This article presents data on the influence of enzymatic activity serum processes liver fibrosis in patients with non-alcoholic fatty disease (NAFLD) and chronic obstructive pulmonary (COPD). Clinical, biochemical, immunological research methods enzyme-linked immunosorbent assay (ELISA) were used work. All determined for degree using a non-invasive method – Fibromax. It was found that NAFLD COP...

Background Rheumatoid arthritis (RA) is a chronic, systemic disorder characterized by the presence of many proinflammatory cytokines that have been involved in pathogenesis, comorbidity, and premature mortality, due to increased atherosclerotic heart disease[1]. homocysteinemia an independent risk factor for coronary disease, stroke, predictor cardiovascular mortality patients.[2] leptin compon...

Increasing evidence points to a causal involvement of inflammation in the pathogenesis neuropsychiatric disorders, including major depressive disorder (MDD) and schizophrenia (SZ). Neopterin biopterin may link peripheral immune system activation central neurotransmitter alterations. However, it is not fully established whether these alterations are transdiagnostic or disorder-specific they asso...

There is increasing evidence that renal disease is presumed to be one of the main causes of mortality among rheumatoid arthritis (RA) patients. Thus, it is important to periodically carryout sensitive and reliable measures for renal function to pickup the earliest signs of renal dysfunction. In this regard, the aim of the present work is to look for the most predictable urinary index for early ...

the aim of this cross-sectional study was to explore the association of crystalline silica aerosols exposure with malondialdehyde in blood serum and urinary neopterin and explore their potential as biomarkers of their external exposure. nonsmoking and healthy male glass sandblasters and control population were randomly selected for this study. all groups were monitored for their personal exposu...