The reversal of the inhibitory action of antiseptics by substances showing a specific affinity for the inhibiting agent has been reported for many compounds, the most striking effect probably being the reversal of the action of mercurials by H2S, glutathione, sodium thioglycolate, etc. Valko and DuBois (1944) have reported that the germicidal action of cationic detergents against both gram-posi...

this study was carried out to evaluate the antimicrobial and antioxidant effectiveness of different extracts from aerial parts of six salvia species including salvia ceratophylla, salvia chorassanica, salvia leriifolia, salvia macrosiphon, salvia chloroleuca and salvia virgata. the effect of the extracts against 3 gram positive and 3 gram negative bacteria was tested by the micro dilution metho...

The activities of OPT-80 against 453 intestinal bacteria were compared with those of seven other drugs. OPT-80 showed good activity against most clostridia, staphylococci, and enterococci, but streptococci, aerobic and facultative gram-negative rods, anaerobic gram-negative rods, and Clostridium ramosum were resistant. Poor activity against anaerobic gram-negative rods may maintain colonization...

OBJECTIVES Respiratory infections with multidrug-resistant (MDR) bacteria are life-threatening in patients with cystic fibrosis (CF). Squalamine and aminosterol derivatives (ASDs) have previously demonstrated interesting antibacterial activity against bacterial reference strains. This study investigated for the first time their activity against MDR clinical isolates recovered from the sputa of ...

The chemical compositions, antioxidant and antimicrobial properties of fucoidan extracted from Sargassum ilicifolium and S.angustifolium were investigated. The results showed that these seaweeds were characterized by an acceptable level of minerals and proteins. The fatty acid profile was dominated by the palmitic acid, which represents about 37.44±0.01% and 23.05±0.01% of the total fatty acids...

The calixarene derivative used in this study (tetra-p-guanidinoethylcalix[4]arene) shows vitro activity against different Gram-positive and Gram-negative bacteria. interaction between bacterial cell membranes the water-soluble was investigated using model lipids spread as monomolecular films at air–water interface. Compression adsorption experiments, well Brewster angle microscopy, polarization...

BACKGROUND The growth-inhibiting and morphostructural effects of seven constituents identified in Asarum heterotropoides root on 14 intestinal bacteria were compared with those of the fluoroquinolone antibiotic ciprofloxacin. METHOD A microtiter plate-based bioassay in sterile 96-well plates was used to evaluate the minimal inhibitory concentrations (MICs) of the test materials against the or...

Cefatrizine, a new oral semisynthetic cephalosporin, was evaluated in vitro and in the treatment of 18 patients with acute urinary tract infection, pneumonia, and soft tissue infection. In vitro, it was more active than cephalexin for gram-positive and gram-negative bacteria. It was also more active than cephalothin, cefazolin, and cephapirin against most of the gram-negative bacteria but less ...

Using PS-5 as starting material, the effects of chemical modification at the C-3 side chain were studied on the antibacterial activity against Gram-positive and Gram-negative bacteria including beta-lactamase-producers. Among 35 side chains tested, 4-pyridylthio showed the highest antibacterial activity against the Gram-positive bacteria, and D-cysteinyl against the Gram-negative microbes. In g...