نتایج جستجو برای: nano vesicles
تعداد نتایج: 92035 فیلتر نتایج به سال:
We report an approach to spatially resolve the content across nanometer neuroendocrine vesicles in nerve-like cells by correlating super high-resolution mass spectrometry imaging, NanoSIMS, with transmission electron microscopy (TEM). Furthermore, intracellular electrochemical cytometry at nanotip electrodes is used to count the number of molecules in individual vesicles to compare to imaged am...
Cell-derived microparticles (MPs) are nano-sized vesicles released by activated cells in the extracellular milieu. They act as vectors of biological activity by carrying membrane-anchored and cytoplasmic constituents of the parental cells. Although detection and characterization of cell-derived MPs may be of high diagnostic and prognostic values in a number of human diseases, reliable measureme...
Bactericidal/permeability-increasing protein (BPI) had been shown to possess anti-inflammatory and endotoxin neutralizing activity by interacting with LPS of Gram-negative bacteria. The current study examines the feasibility of using murine BPI (mBPI) expressed on halophilic Archaeal gas vesicle nanoparticles (GVNPs) for the treatment of endotoxemia in high-risk patients, using a murine model o...
The identification of extracellular vesicles (EVs) as intercellular conveyors of biological information has recently emerged as a novel paradigm in signaling, leading to the exploitation of EVs and their contents as biomarkers of various diseases. However, whether there are diurnal variations in the size, number, and tissue of origin of blood EVs is currently not known, and could have significa...
چکیده برهمکنش یون های فلزی با پروتئین ها مورد توجه بسیاری از محققین، خصوصا بیوشیمی-دانان قرار گرفته است. آمینو اسیدها، بلوک های ساختمانی پروتئین ها هستند. پروتئین ها که مرکب از آمینواسیدها هستند نقش اساسی در بسیاری از متابولیسم های بدن دارند. در این کار، میزان پایداری کمپلکس های تشکیل شده از آمینواسیدهای فنیل آلانین و تریپتوفان با وانادیوم (v) و نانووانادیوم اکسید را در آب و مخلوط حلال آب- دی...
Developing new functional biomaterials from biocompatible natural-based resources for gene/drug delivery has attracted increasing attention in recent years. In this work, we prepared a series of cationic nanoparticles (Diosarg-DOPE NPs) by assembly of a natural steroid diosgenin-based cationic lipid (Diosarg) with commercially-available helper lipid 1,2-dioleoyl-sn-glycero-3-phosphorethanolamin...
objective: maintaining the health of oral tissues is a major goal in dentistry. however, limitations in dental materials, instruments, procedures and medications prevent achievement of this goal. advances in nanotechnology have paved the way to approach this goal. this study reviews the advances on nanotechnology in dentistry. review of literatures: in this review study, google scholar, pubmed,...
The goal of the current study was to explore the potential benefits of Acitretin (Act) nanovesicular gel as a prospective antipsoriatic topical delivery system counteracting the drug challenges in terms of its extremely low aqueous solubility, instability, skin irritation, and serious systemic adverse effects. Act-loaded niosomes were successfully developed, entirely characterized, and optimize...
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