Most healthy children shrug off viral respiratory tract infections with little difficulty or assistance and a full recovery is the norm. A small minority, in contrast, are left with serious consequences. Important among these is postinfectious bronchiolitis obliterans (pBO) characterised by persistent—and sometimes severe—airway obstruction with functional and radiological evidence of small air...

OBJECTIVE To compare the rates of physical, psychiatric, and suicide-related events in adolescents with MDD treated with fluoxetine alone (FLX), cognitive-behavioral therapy (CBT), combination treatment (COMB), or placebo (PBO). METHOD Safety assessments included adverse events (AEs) collected by spontaneous report, as well as systematic measures for specific physical and psychiatric symptoms...

OBJECTIVE To evaluate the validity of enthesitis indices in patients with peripheral spondyloarthritis (pSpA). METHODS The ABILITY-2 study evaluated the efficacy of adalimumab (ADA) versus placebo (PBO) in patients with active pSpA over 12 weeks. Patients received open-label ADA for an additional 144 weeks. Twenty-nine enthesitis sites used in 3 enthesitis scoring systems [Leeds Enthesitis In...

Diazinon, an organophosphate pesticide, becomes biotransformed to a more potent oxon metabolite that inhibits acetylcholinesterase (AChE). Early life stages (els) of medaka, Oryzias latipes, were used to determine how development of this teleost affects sensitivity to diazinon. With developmental progression, from day of fertilization to 7-day-old larvae, we found that the 96-h LC50 and AChE IC...

Background. This study was undertaken to determine relative contributions of phosphorylation and oxidation to the increased activity of calcium/calmodulin-stimulated protein kinase II (CaMKII) in juveniles with cardiac myocyte dysfunction due to increased pressure overload. Methods. Juvenile rats underwent abdominal aortic constriction to induce heart failure. Four weeks after surgery, rats wer...

Recent agrochemical usage patterns suggest that the use of organophosphate (OP) pesticides will decrease, resulting in a concomitant increase in pyrethroid usage. Pyrethroids are known for their potential toxicity to aquatic invertebrates and many fish species. Current toxicity identification evaluation (TIE) techniques are able to detect OPs, but have not been optimized for pyrethroids. Organo...

PURPOSE To examine the effects of a whole-body cryotherapy (WBC) protocol (3 min at -110°C) on acute recovery and key variables of endurance performance during high-intensity intermittent exercise in a thermoneutral environment. METHODS Eleven endurance athletes were tested twice in a randomized crossover design in which 5×5 min of high-intensity running (HIR) were followed by 1 h of passive ...

In an effort to combat West Nile Virus, planes dispersed insecticide over Sacramento, CA, treating nearly 50,000 hectares with pyrethrins and the synergist piperonyl butoxide (PBO). Widespread dispersal of insecticide over a metropolitan area, coupled with extensive pretreatment data on the area's urban creeks, provided a unique opportunity to study effects of mosquito control agents on aquatic...

1 緒 言 PBO(ポリパラフェニレンベンゾビスオキサゾ-ル) 繊維は,繊維強化複合材料の有機系強化繊維の一つであ り,炭素繊維に匹敵する強度・弾性率を有し,有機繊維 中最高の耐熱性・難燃性を示す事から,FRPの次世代の 強化繊維としての用途展開が期待されている.1), 2) しかしながら,PBO繊維は,繊維/樹脂間の界面強度 が不十分であり,この界面強度は FRPの様々な力学的特 性に大きく影響するため,3)PBO繊維の FRPの強化繊維と しての優れた特性を最大限に活かすためには,界面強度 向上を目的とした繊維表面改質法の研究が不可欠となっ てくる. 現在,繊維/樹脂間の界面強度の向上を目的として, 様々な表面改質法が試みられている.中でも低温プラズ マ処理は,ドライプロセスで低公害であり,繊維自身の 物性を損なうことなく,親水性の官能基を表面に効率的 に付与できるといった利点を...