Estimation of sediment transport load due to erosion in river basins is one of the issues which is indispensable for many projects related to water resources, soil and damps construction. With regards to the phenomenon of erosion and transmission Sedimentation in rivers has always led to deformation in the seaboard and sedimentation, so the management and planning in bank of rivers is important...

1 Direct search optimization Problems in the paper (SOF) Other problem, without gradient Aim of this work: Putting forward a class of optimization methods largely overlooked in systems and control: the direct search methods. They can however be very adequate and powerful for many complex problems (possibly including yours).

format. All authors have approved the final version of the article. There are no conflicts of interest to declare. We thank the reviewers for their constructive comments and hope that you find our revised manuscript suitable for publication in BMC Nephrology. Yours sincerely, on behalf of the co-authors,

There are various ways to teach people be able hope and rely on God. Behold, LORD, who among the gods is like you? Who you, wonderful in holiness? can work miracles mighty acts yours? This article argues that song of Moses teaches faith lesson. The miracle God brings healing comfort. Therefore, God’s deliverance should encourage trust Lord more their difficulties. 

Sincerely yours, Xiulan Zhang, MD, PhD Professor of Ophthalmology, Vice director of Glaucoma Department, Director of Clinical Research Center, Director of Institution of Drug Clinical Trials, Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University 54S.Xianlie Road, Guangzhou, China 510060 Email: [email protected]. Tel: +86-20-87330484 Fax: +86-20-87333...

Sincerely yours, Xiulan Zhang, MD, PhD Professor of Ophthalmology, Vice director of Glaucoma Department, Director of Clinical Research Center, Director of Institution of Drug Clinical Trials, Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University 54S.Xianlie Road, Guangzhou, China 510060 Email: [email protected]. Tel: +86-20-87330484 Fax: +86-20-87333...

ABSTRACT Advances in Nuclear Magnetic Resonance (NMR) spectroscopy is a cornerstone structure elucidation of polycyclic 'cage' scaffolds. Due to the compactness these compounds, much overlap, as well unique through-space and bond NMR interactions are frequently observed. This review serves guide for future derivatives by providing some typical relevant aspects characteristic trends, substituent...