In the title compound, C(11)H(13)NO(3), the conformations of the N-H and C=O bonds in the amide segment are anti to each other. Further, the conformations of the amide and carbonyl O atoms of the acid segment are also anti to the adjacent -CH(2) groups. The C=O and O-H bonds of the acid group are syn to each other. In the crystal, mol-ecules are packed into infinite chains along the b axis thro...

N-Glycolylneuraminic acid (Neu5Gc) is an oncofetal antigen in humans and is developmentally regulated in rodents. We have explored the biology of N-acetylneuraminic acid hydroxylase, the enzyme responsible for conversion of the parent sialic acid, N-acetylneuraminic acid (Neu5Ac) to Neu5Gc. We show that the major sialic acid in all compartments of murine myeloma cell lines is Neu5Gc. Pulse-chas...

In the title compound, C(11)H(11)NO(3), the conformation of the N-H bond is anti to the C=O bond in the amide segment, while it is syn to the ortho-methyl group in the phenyl ring. In the maleamic acid unit, the amide C=O bond is anti to the adjacent C-H bond, while the carboxyl C=O bond is syn to the adjacent C-H bond. The C=O and O-H bonds of the acid group are in the relatively rare anti pos...

In the title compound, C(10)H(8)ClNO(3), the molecular conformation is stabilized by two intra-molecular hydrogen bonds. The first is a short O-H⋯O hydrogen bond within the maleamic acid unit and the second is a C-H⋯O hydrogen bond which connects the amide group with the phenyl ring. The maleamic acid unit is essentially planar, with an r.m.s. deviation of 0.044 Å, and makes a dihedral angle of...

The conformations of the N-H and C=O bonds in the amide segment of the structure of the title compound {systematic name: 3-[(2-chloro-phen-yl)amino-carbon-yl]propionic acid}, C(10)H(10)ClNO(3), are trans to each other, while the conformation of the amide H atom is syn to the ortho-chloro group in the benzene ring. Further, the conformations of the amide O atom and the carbonyl O atom of the est...

In the amide segment of the title compound, C(12)H(15)NO(3) {systematic name: 3-[(2,6-dimethyl-phen-yl)amino-carbon-yl]propionic acid}, the N-H and C=O bonds are anti to each other. The mol-ecules are packed into a two-dimensional array via N-H⋯O and O-H⋯O hydrogen bonds.

In the crystal structure of the title compound, C(11)H(10)N(2)O(3), inversion-related mol-ecules are connected by pairs of O-H⋯O hydrogen bonds. With the exception of the atoms in the carb-oxy-lic acid group, the non-H atoms are roughly coplanar with a maximum deviation from the mean plane of 0.270 (1) Å for the C atom to which the carb-oxy-lic group is attached. The C atom of the carb-oxy-lic ...

In the crystal of the title compound, C(10)H(9)Cl(2)NO(3), the conformations of the amide O atom and the carbonyl O atom of the acid segment are anti to each other and to the H atoms on the adjacent -CH(2) groups. The C=O and O-H bonds of the acid group are syn to one another. In the crystal, mol-ecules are packed into infinite chains through inter-molecular O-H⋯O and N-H⋯O hydrogen bonds.

In the crystal structure of the title compound, C(10)H(6)Cl(3)NO(3), the conformation of the amide bond is trans. The C=O and O-H bonds of the acid group are in the relatively rare anti position to each other. This is a consequence of the intra-molecular O-H⋯O hydrogen bond donated to the amide carbonyl group stabilizing the mol-ecular structure. In the crystal, inter-molecular N-H⋯O hydrogen b...

The asymmetric unit of the title compound, C(12)H(13)NO(3), contains two independent mol-ecules. The conformation of the N-H bond and the C=O bond in the amide segment are anti to each other. The mol-ecular conformation of each mol-ecule is stabilized by an intra-molecular O-H⋯O hydrogen bond. In the crystal, mol-ecules are connected through intermolecular N-H⋯O hydrogen bonds. In addition, the...