Ichihara, Atsuhiro, and L. Gabriel Navar. Neuronal NOS contributes to biphasic autoregulatory response during enhanced TGF activity. Am. J. Physiol. 277 (Renal Physiol. 46): F113–F120, 1999.—To assess the afferent arteriolar autoregulatory response during increased activity of the tubuloglomerular feedback (TGF) mechanism and to delineate the contribution of neuronal nitric oxide synthase (nNOS...

Wasserstrom, J. Andrew, and Ana-Maria Vites. Activation of contraction in cat ventricular myocytes: effects of low Cd21 concentration and temperature. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H488–H498, 1999.—The effects of Cd21 (20 μM) and different bath temperatures were used to study the contributions of two separate triggering mechanisms, L-type Ca21 current (ICa) and reverse mode Na1...

Murer, Heini, Ian Forster, Nati Hernando, Georg Lambert, Martin Traebert, and Jürg Biber. Posttranscriptional regulation of the proximal tubule NaPi-II transporter in response to PTH and dietary Pi. Am. J. Physiol. 277 (Renal Physiol. 46): F676–F684, 1999.—The rate of proximal tubular reabsorption of phosphate (Pi) is a major determinant of Pi homeostasis. Deviations of the extracellular concen...

Kalhorn, Thomas, and Richard A. Zager. Renal cortical ceramide patterns during ischemic and toxic injury: assessments by HPLC-mass spectrometry. Am. J. Physiol. 277 (Renal Physiol. 46): F723–F733, 1999.—Ceramides are a class of signaling molecules that can acutely accumulate in tissues as part of a ‘‘stress response.’’ They are classically measured by the diacylglycerol kinase assay, which, in ...

Choudhry, Mashkoor A., Philip E. Hockberger, and Mohammed M. Sayeed. PGE2 suppresses mitogen-induced Ca21 mobilization in T cells. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R1741–R1748, 1999.—PGE2mediated suppression of T cell proliferation during sepsis could result from altered Ca21 signaling. The present study evaluated the effects of PGE2 on Ca21 release from intracell...

Hines, Wirt A., Jacqueline Thorburn, and Andrew Thorburn. Cell density and contraction regulate p38 MAP kinase-dependent responses in neonatal rat cardiac myocytes. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H331– H341, 1999.—In vitro cardiac myocyte hypertrophy is characterized by increased cell size, sarcomere organization, and induction of several genes including atrial natriuretic facto...

Pflueger, Axel C., Timothy S. Larson, Siegfried Hagl, and Franklyn G. Knox. Role of nitric oxide in intrarenal hemodynamics in experimental diabetes mellitus in rats. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R725–R733, 1999.—The role of nitric oxide (NO) in the regulation of the intrarenal microcirculation in streptozotocin (STZ)-induced diabetes mellitus in rats is not c...

Schwartz, Gary J., Andrew Whitney, Chris Skoglund, Thomas W. Castonguay and Timothy H. Moran. Decreased responsiveness to dietary fat in Otsuka Long-Evans Tokushima fatty rats lacking CCK-Areceptors. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R1144– R1151, 1999.—Adult Otsuka Long-Evans Tokushima fatty (OLETF) rats lack functional cholecystokinin A (CCK-A) receptors, are dia...

Korthuis, Ronald J., Dean C. Gute, Frank Blecha, and Chris R. Ross. PR-39, a proline/arginine-rich antimicrobial peptide, prevents postischemic microvascular dysfunction. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H1007– H1013, 1999.—We and others have previously demonstrated that intestinal ischemia-reperfusion (I/R) is associated with a large increase in oxidant production that contribute...

Rinaman, Linda. Interoceptive stress activates glucagonlike peptide-1 neurons that project to the hypothalamus. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R582–R590, 1999.—This study tested the hypothesis that systemic stressors in rats activate glucagon-like peptide-1 (GLP-1)-immunoreactive neurons in the caudal brain stem, including those that project to the paraventricul...