although thallium-201 exercise scintigraphy has been established for the detection of myocardial ischemia and viability, little is known regarding the myocardial thallium-201 kinetics during angioplasty. herein, we report a 77-year old man with angina pectoris, in whom serial myocardial imaging after a single dose of thallium-201 was helpful in identifying not only the culprit lesion and myocar...

background: early clinical investigations indicate that an infusion of autologous bone-marrow cells into the infarct-related coronary artery is feasible after acute myocardial infarction. there is increasing evidence that cell transplantation may improve the perfusion and contractile function of the ischemic myocardium . the present study reports primarily the safety of intracoronary bone marro...

A 53-year-old male patient with a previous diagnosis of situs inversus with mirror-image dextrocardia underwent thallium-201 (Tl-201) stress-redistribution myocardial perfusion single photon emission computed tomography (SPECT). Electrocardiogram (ECG) obtained on right hemithorax revealed constant complete left bundle branch block. Tl-201 stress-redistribution SPECT images revealed abnormal pe...

Background CMR perfusion (CMRP) imaging using adenosine traditionally requires bilateral arm cannulation. Patients with multiple comorbidities often have difficult venous access and dual cannulation often proves impossible. We used a standard two-way adapter (Octopus Vygon with no-reflow valve) to administer adenosine at a standard rate of 140 mcg/kg/minute over 3 minutes for maximum coronary v...

A 67 years old woman was referred to nuclear medicine center for myocardial perfusion imaging (MPI) for assessment of ischemic heart dieses (IHD).She had a history of atypical chest pain and dyspnea since about 10 days before admission. The MPI SPECT/CT was performed by stress/redistribution Tl-201 protocol. MPI was interpreted as relatively good coronary flow with no appreciable stress induced...

PURPOSE Different centers and vendors use different sequences and contrast agent application schemes for MR myocardial perfusion imaging. The purpose of this study was to evaluate the role of different sequences, dosages, and injection speeds of contrast media for semiquantitative MR-perfusion assessment. METHODS In a pilot study with 58 consecutive patients three of the most commonly used se...

This paper describes a fully automatic registration of 10 multi-slice myocardial perfusion magnetic resonance image sequences. The registration of these sequences is crucial for the clinical interpretation, which currently is subjected to manual labour. The approach used in this study is a nonrigid registration algorithm based on free-form deformations due to Rueckert et al. Inspection of diffe...

abstract objective: abnormal values of the transient ischemic dilation (tid) ratio are associated with severe and extensive coronary artery disease (cad). tid can be used as a diagnostic and prognostic marker of cad in diabetic patients. the aim of current study was to determine the pooled estimate of tid ratio in single myocardial perfusion scan in diabetic patients by a systematic review and ...

Estimation of the tissue perfusion parameters using ultrasound contrast agent can help to improve diagnosis occlusion of coronary arteries thus it can helps to prevent myocardial infarction. Precise registration of ultrasound time sequence is precondition for automatic and reliable perfusion analysis. Many image registration methods were developed, but ultrasound image registration is a still a...

BACKGROUND We hypothesized that asymptomatic persons with a parent or sibling with coronary artery disease (CAD) have myocardial perfusion defects on positron emission tomography (PET) as markers of early CAD. METHODS AND RESULTS After medical and family histories were recorded, 90 subjects underwent rest-dipyridamole cardiac PET perfusion imaging, including 18 index cases (a subject with CAD...