نتایج جستجو برای: mycophenolate
تعداد نتایج: 3599 فیلتر نتایج به سال:
Introduction: Mycophenolic acid(MPA), a fungal mycotoxin, is produced by Penicillium brevicompactum and is used for the synthesis of immunosuppressive drugs in pharmaceutical industries. The present study was conducted to evaluate the possibility of mycophenolic acid(MPA) production by standard strains of P. brevicompactum at laboratory level. Methods: Three strains of P. brevicompactum were ...
Mixed dissociation constants of four drug acids, i.e. silychristin, silybinin, silydianin and mycophenolate at various ionic strengths I of range 0.01 and 0.30 and at temperatures of 25 and 37 ◦C were determined using the SQUAD(84) regression analysis program applied to pH-spectrophotometric titration data. The proposed strategy of an efficient experimentation in a protonation constants determi...
BACKGROUND We assess our long-term experience with regards the safety and efficacy of Mycophenolate Mofetil (MMF) in our low risk renal transplant population and compared it retrospectively to Azathioprine (AZA) immunosuppressive regimen. Patients and methods. Between January 1999 and December 2005, 240 renal transplants received MMF as part of their immunosuppressive protocol (MMF group). AZA...
We describe the experience of the focal segmental glomerulosclerosis clinical trial (FSGS CT) in the identification and recruitment of participants into the study. This National Institutes of Health funded study, a multicenter, open-label, randomized comparison of cyclosporine versus oral dexamethasone pulses plus mycophenolate mofetil, experienced difficulty and delays meeting enrollment goals...
Despite numerous randomized clinical trials over the last three decades for identifying the optimal treatment option for lupus nephritis, renal involvement still significantly impacts the survival and quality of life of patients with lupus and the search for the ideal immunosuppressive regimen is far from complete. The purpose of this review is to summarize the major recent achievements in the ...
A wide range of treatments are currently available for severe atopic dermatitis, including systemic therapies such as ciclosporin, corticosteroids, azathioprine, methotrexate, mofetil mycophenolate, and omalizumab. In patients who can no longer take systemic drugs or who need a dose reduction, wet-wrap treatment can be an excellent option. To date, wet wraps have mostly been used in severe case...
The achievements in photoimmunology over the last years have not only broadened our knowledge how ultraviolet (UV) light compromises the immune system but have also yielded important insights into general immunology and photobiology. Therefore, studies will not only increase our understanding how UV acts as a pathogen but will also support the development of new therapeutic strategies, e.g. sup...
A 21-year-old female presenting linear IgA and IgG disease initially responded well to dapsone therapy. However, the treatment with dapsone was withdrawn due to severe anemia induced by malaria, which led to worsening of the clinical picture. Although prednisone and methylprednisolone were tried, the patient responded only to the association of dapsone and mycophenolate mofetil.
haematologica/journal of hematology vol. 88(07):july 2003 837 Beguin Research Director of the National Fund for Scientific Research (FNRS, Belgium). This work was supported by grants from “La Fondation BonjeanOleffe”, “L’Association sportive contre le cancer”, “Le Fonds de Recherche Scientifique du CHU Sart-Tilman” and the National Fund for Scientific Research (FNRS, Belgium). Correspondence: Y...
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