An 8-year-old female patient was referred to a paediatrician for assessment of an episode of global muscle weakness after a 100 m sprint. There was no loss of consciousness. Proximal hip muscles and shoulder girdle weakness was noted and the possibility of a myopathy was raised. Muscle biopsy demonstrated “ultra-structurally normal muscle fibres”. There was indolent progression of proximal musc...

Muscular dystrophies are a genetically heterogeneous group of degenerative muscle disorders. It characterized by progressive muscle wasting and weakness of variable distribution and severity. There are several subgroups including Duchenne/Becker, fascioscapulohumeral, limb-girdle, oculopharngeal, and congenital muscular dystrophy. Diagnosis is dependent to the characteristic clinical features i...

The periodic paralyses are hereditary muscle diseases which cause both episodic and permanent weakness. Permanent weakness may include both reversible and fixed components, the latter caused by fibrosis and fatty replacement. To determine the degree of handicap and impact of permanent weakness on daily life, we conducted a 68-question online survey of 66 patients over 41 years (mean age, 60 ± 1...

Neurological deficit due to Vertebroplasty cement leakage as an important complications with early sign and symptom but delay radicular pain muscle weakness presentation was rare need correct diagnostic approach.