The purpose of the study was to determine the influence of preseason lower-extremity range of motion (ROM) on the risk of muscle strain injury during a competitive season for elite soccer players. Thirty-six elite male soccer players (age, 25.6 +/- 4.7 years) had maximum static ROM for 6 movements of the lower extremity measured prior to the 2003-2004 English Premier League season. Player age, ...

Beitzel, Felice, Paul Gregorevic, James G. Ryall, David R. Plant, Martin N. Sillence, and Gordon S. Lynch. 2-Adrenoceptor agonist fenoterol enhances functional repair of regenerating rat skeletal muscle after injury. J Appl Physiol 96: 1385–1392, 2004. First published November 7, 2003; 10.1152/japplphysiol.01081.2003.— 2-Adrenoceptor agonists such as fenoterol are anabolic in skeletal muscle, a...

Abstract Macrophages promote skeletal muscle homeostasis by participating in crosstalk with satellite cells, fibroadipogenic precursors, and myofibers that drives regeneration after injury. Dysregulation of this contributes to conditions like myopathy, inefficient wound healing, sarcopenia. Despite their central role regeneration, the tissue-intrinsic mechanisms coordinate recruitment activity ...

Contusion injuries in skeletal muscle commonly occur in contact sport and vehicular and industrial workplace accidents. Icing has traditionally been used to treat such injuries under the premise that it alleviates pain, reduces tissue metabolism, and modifies vascular responses to decrease swelling. Previous research has examined the effects of icing on inflammation and microcirculatory dynamic...

Use of mild hyperbaric oxygen less than 2 atmospheres absolute (2026.54 hPa) with normal air is emerging as a common complementary treatment for severe muscle injury. Although hyperbaric oxygen at over 2 atmospheres absolute with 100% O2 promotes healing of skeletal muscle injury, it is not clear whether mild hyperbaric oxygen is equally effective. The purpose of the present study was to invest...

Stereology was used to investigate the changes in ultrastructure of smooth muscle cells during the formation of an experimental intimal thickening induced by injury with an inflated balloon catheter. The volume density of myofilaments in the cell cytoplasm was measured in smooth muscle cell-lined areas (which are freely permeable to Evans blue dye and, hence, stain blue) and in re-endothelializ...

The expression of laminin isoforms and laminin-binding integrin receptors known to occur in muscle was investigated during myogenic regeneration after crush injury. Comparisons were made between dystrophic 129ReJ dy/dy mice, which have reduced laminin alpha2 expression, and their normal littermates. The overall histological pattern of regeneration after crush injury was similar in dy/dy and con...

Introduction and Purpose The muscle injury grading systems are based in part on ultrasound (US) and magnetic resonance imaging (MRI). However, the prognosis by MRI is not clear. There is evidence that part of the return-to-play is conditioned by the severity of the injury [1], and in our experience, this severity is associated with muscle gap (quantifiable retraction between fibers). Recently, ...

The hamstring muscle group is a vital constituent to injury prevention and lower extremity rehabilitation. During closed chain activity, hamstring muscle fibers influence dynamic interaction between the pelvis, sacrum, femur and lower leg. The hamstring muscle group functions as a frontal and transverse plane stabilizer, influencing knee flexion deceleration and eccentric extension during forwa...

Prevention of infection, as well as bone covering and healing, is paramount in the management of limb injury with associated muscle injury. Volumetric muscle loss (VML) is the traumatic or surgical loss of skeletal muscle with resultant functional impairment. No standardized evaluation protocol exists for the characterization and quantification of VML. Clinical photographs and video recordings,...