BACKGROUND Inflammation is thought to be involved in the pathogenesis of obstructive sleep apnea syndrome (OSAS). Hepcidin, a 25-kD peptide hormone produced by the liver, modulates acute inflammatory responses. This study aimed to determine the association of serum levels of hepcidin with the presence and severity of OSAS. MATERIAL/METHODS We enrolled 184 patients with OSAS and 110 healthy su...

STUDY OBJECTIVE Sleep-disordered breathing (SDB) is a prevalent condition in children and is associated with increased cardiovascular morbidity. Circulating levels of C-reactive protein (CRP), a proinflammatory protein, are associated with increased risk for atherosclerosis. Plasma CRP levels in snoring children have yielded conflicting results, such that it remains unclear whether OSA is mecha...

Obstructive sleep apnea causes intermittent elevation of systemic blood pressure (BP) during sleep. To determine whether obstructive apnea in children has a tonic effect on diurnal BP, 24-hour ambulatory blood pressure was obtained from 60 children with mean age of 10.8 +/- 3.5 years. Thirty-nine children had obstructive apnea and 21 had primary snoring. Children with obstructive apnea had sign...

BACKGROUND Obstructive sleep apnea is characterized by intermittent hypoxia and hypercapnia. CO2 production, transport and elimination are influenced by the carbonic anhydrase enzyme. We hypothesized that elevated standard bicarbonate, a proxy for increased carbonic anhydrase activity, is associated with apnea severity and higher blood pressure in patients with obstructive sleep apnea. METHOD...

BACKGROUND Previous studies have documented a high prevalence of atrial fibrillation (AF) in individuals with obstructive sleep apnea (OSA). Central sleep apnea (CSA) has been associated with AF in patients with heart failure. However, data from prospective cohorts are sparse and few studies have distinguished the associations of obstructive sleep apnea from CSA with AF in population studies. ...

background: sleep apnea is associated with increased risk ofdiabetes mellitus. however, no studies have compared sleep apneasymptoms in diabetic patients and their first degree relatives.the purpose of our study was to investigate high risk for sleepapnea syndrome, in diabetics and their first degree relatives forprevention of diabetes in family.methods: as a part of a cohort study, all of diab...

Abstract West Sumatra is one of the provinces that have potential to be used as a rice production center in Indonesia. However, determination local centers still justified based on conventional methods. This study aims obtain historical data variables, process using K-Means algorithm (RStudio), and justify areas given year acquisition recommendation values (centroids). The results showed 2010-2...

OBJECTIVE In this study, we assessed the efficacy of a new method (expansion sphincter pharyngoplasty [ESP]) to treat obstructive sleep apnea. STUDY DESIGN We conducted a prospective, randomized controlled trial. METHODS Forty-five adults with small tonsils, body mass index less than 30 kg/m2, of Friedman stage II or III, of type I Fujita, and with lateral pharyngeal wall collapse were sele...