PURPOSE To quantify the extent of visual function losses in patients with North Carolina Macular Dystrophy (NCMD) and to demonstrate the importance of accounting for eccentric fixation when making comparisons with normal data. METHODS Five patients with NCMD who were from a single family were examined. Multifocal electroretinograms (mfERGs) and psychophysical assessments of acuity and luminan...

PURPOSE To determine the features of wide-field multifocal electroretinography (WF-mfERG) recorded in patients with central retinal vein occlusion (CRVO) and to compare WF-mfERG responses of the affected and fellow eyes. In addition, WF-mfERG responses were also compared by using standard electroretinography (ERG). METHODS WF-mfERG and ERG responses were recorded from both eyes of 56 patients...

Background Nutritional visual defects are apparently uncommon nowadays in developed nations. Retinal change-related caused by hypovitaminoses may be underdiagnosed. Aim of the study To investigate retinal structural and functional changes a patient with multivitamin deficiency before during vitamin supplementation. Methods A 51-year-old female had been on vegetarian diet as child, restrict vega...

Abstract Background The nasal to temporal amplitudes ratio (N/T) of multifocal electroretinography (mfERG) scans measured within 5° the macula can be used detect glaucomatous change. photopic negative response (PhNR) mfERG elicited by a circular stimulus centered on fovea was significantly reduced in eyes with glaucoma. PhNR B-wave (PhNR/B) is optimal measure PhNR. However, clinical superiority...

Purpose: Evaluating the effects of memantine on visual function after scleral buckling for rhegmatogenous retinal detachment (RRD) Methods: In a Double blind prospective randomized clinical trial, 61 patients with clinical diagnosis of less than 4 weeks macula-off RRD who had successful scleral buckle surgery had been selected and divided into two randomized groups. Thirty of them received 5 mg...

PURPOSE To perform a clinical characterization of Stargardt patients with ABCA4 gene mutation, and to investigate the correlation between the inner and outer segment (IS/OS) junction morphology and visual acuity, fundus lesions, electroretinogram abnormalities, and macular sensitivity. METHODS Sixty-one patients with Stargardt disease (STGD) were given a comprehensive ophthalmic examination. ...