Activation of both PAR-1 (proteinase-activated receptor-1) and PAR-2 resulted in release of the chemokine GRO (growth-regulated oncogene)/CINC-1 (cytokine-induced neutrophil chemoattractant-1), a functional counterpart of human interleukin-8, from rat astrocytes. Here, we investigate whether the two PAR receptor subtypes can signal separately. PAR-2-induced GRO/CINC-1 release was independent of...

A reaction model was developed for the pyrolysis of binary mixtures of compounds whose reactions can be apportioned into three or fewer parallel chains coupled by chain transfer. A representative application of this model to the pyrolysis of mixtures of the asphaltene model compounds n-pentadecylbenzene (PDB) and n-tridecylcyclohexane (TDC) illustrates its utility. The model, along with its ass...

Multi-path is favorite alternative for sensor networks, as it provides an easy mechanism to distributetraffic, as well as considerate fault tolerance. In this paper, a new clustering based multi path routingprotocol namely ECRR (Energy efficient Cluster based Routing algorithm for improving Reliability) isproposed, which is a new routing algorithm and guarantees the achievement to required QoS ...

the problem of finding the minimum cost multi-commodity flow in an undirected and completenetwork is studied when the link costs are piecewise linear and convex. the arc-path model and overflowmodel are presented to formulate the problem. the results suggest that the new overflow model outperformsthe classical arc-path model for this problem. the classical revised simplex, frank and wolf and a ...

BACKGROUND The optimal therapy for preventing recurrent stroke in people with cryptogenic stroke and patent foramen ovale (PFO) has not been defined. The choice between medical therapy (antithrombotic treatment with antiplatelet agents or anticoagulants) and transcatheter device closure has been the subject of intense debate over the past several years. Despite the lack of scientific evidence, ...

BACKGROUND Dialysate-based, on-line measurements of Kt/V and protein catabolic rate (PCR) in dialysis patients have been considered more accurate compared with measurements on the blood side during dialysis. The primary aim of this study was to compare total removed urea (TRU) and PCR, normalized to body weight (nPCRw), obtained by three dialysate-based methods: (i) on-line ultraviolet (UV) abs...

OBJECTIVE A less invasive method to assess internal thoracic artery (ITA) graft function after coronary artery bypass grafting (CABG) is desired. This study reports the novel method to estimate ITA graft function using CT angiography. MATERIALS AND METHODS Fifty ITA grafts were assessed. Hounsfield Unit transition of each graft on the same cross section was detected during the Test Bolus Inje...

We describe the construction and characterization of a genomically recoded organism (GRO). We replaced all known UAG stop codons in Escherichia coli MG1655 with synonymous UAA codons, which permitted the deletion of release factor 1 and reassignment of UAG translation function. This GRO exhibited improved properties for incorporation of nonstandard amino acids that expand the chemical diversity...

The Field Programmable Gate Array (FPGA) structure poses several constraints that make the implementation of complex asynchronous circuits such as Time-Mode (TM) almost unfeasible. In particular, in Logic (PL) devices, FPGAs, operation logic is usually synchronous with system clock. However, it can happen a very high-performance specifications demands to abandon this paradigm and follow an impl...

Responses of Cola nitida and acuminata to NPK Super-gro fertilizers on seedling development, field establishment, canopy characteristics were investigated in 2019-2020. Seedlings the two species transplanted as a randomized complete block design with three replications field. Fertilizer treatments imposed shoot root growth parameters cola monitored for growing seasons. From results, application...