Pulmonary tuberculosis with multi-drug resistant Mycobacterium tuberculosis is a major cause of concern in many of the developing countries. The present study was carried out to study the prevalence of multi-drug resistant tuberculosis (MDR-TB) in clinical isolates at DR.PSIMS & RF general hospital in Gannavaram, which is a tertiary care hospital. Two hundred and fifty seven sputum samples were...

Emergence of drug resistant tuberculosis like multi drug resistant tuberculosis (MDR-TB), extensively drug-resistant tuberculosis (XDR-TB) and totally drug resistant tuberculosis (TDR-TB) has created a new challenge to fight against these bad bugs of Mycobacterium tuberculosis. Repurposing and revival of the drugs are the new trends/options to combat these worsen situations of tuberculosis in t...

This thesis examines the contrasting roles of genetic drift and selection on the emergence of drug resistance in Mycobacterium tuberculosis. In clinical practice some alleles of rifampicin resistance are isolated more frequently than others. To identify if this variation is due to genetic drift or selection, the mutation rate to rifampicin resistance in M. tuberculosis (H37Rv) was determined. P...

OBJECTIVES To estimate the resistance rate and to correlate the clinical characteristics of resistant tuberculosis with the patients of pulmonary tuberculosis who were referred to the university hospital. METHODS We prospectively performed sensitivity tests for all patients who were diagnosed as active tuberculosis by sputum smear or sputum culture from January, 1995 to June, 1996. Patients p...

the increasing incidence of multi drug resistance tuberculosis (mdr-tb) and extensively drug resistance tb (xdr-tb) worldwide highlight the urgent need to search for newer anti-tuberculosis compounds. it has been determined that pharmaceutical plant, hops ( humulus lupulus ), possesses some antibacterial effect. in this study, the antimycobacterial effect of this plant on rifampin sensitive and...

A cross-sectional study was conducted on street-vended food randomly from different areas of Kathmandu Valley to assess the number viable bacteria in street food, distribution bacteria, antibiotics resistance profile isolated Methicillin-resistant S. aureus (MRSA), and Vancomycin-Resistant (VRSA) valley. Altogether 339 isolates were identified one hundred eighty (180) samples. The average mean ...

Based on data from the Global Tuberculosis Report 2020, it is known that 1.4 million people died tuberculosis. Indonesia ranked third in world with 845,000 cases. It estimated as many 24,000 cases of drug-resistant tuberculosis each year, Multi Drug Resistant (MDR). An initial survey conducted work area UPT Puskesmas Tanjung Morawa found complete treatment rate for all was 60%. One indicators s...