Discrete papular lichen myxedematosus (DPLM), asubset of localized lichen myxedematosus, is a rarecutaneous mucinosis of unknown etiology. We reporta case of a 57-year-old woman with palmoplantarpsoriasis who developed DPLM 8 weeks after addingustekinumab to a long-term course of methotrexate.The patient had previously failed 2 prior tumor necrosisfactor (TNF) inhibitors, adalimumab and etanerc...

IMPORTANCE Self-healing juvenile cutaneous mucinosis is a very rare, self-limiting disease characterized by the abrupt onset of asymptomatic papules and nodules located primarily on the face and periarticular regions of a juvenile patient. There have been less than 20 cases reported since it was first described in 1973. OBSERVATIONS Most cases have been reported in children 15 years and young...

Oral focal mucinosis (OFM) is a rare soft tissue lesion of unknown etiology. Clinically, it is most commonly found on the gingiva and presents as a painless, sessile or pedunculated mass of the same colour as the surrounding mucosa. Histologically, it is characterized by focal myxoid degeneration of connective tissue. OFM occurs predominantly in adults during the fourth and fifth decade of life...

We report the successful treatment of plaque-like sclerodermiform mucinosis using tacrolimus ointment topically. We present a 70-year-old male with a large chronic erythema and hardening of the nuchal skin and shoulder area. Subjective symptoms were a moderate pruritus and a rather disabling stiffness. A biopsy specimen revealed typical features of lichen myxedematosus. In a subsequent clinical...

1 Ex-professor titular e atual médico voluntário da Santa Casa de São Paulo São Paulo (SP), Brasil. Em 1916, Dossekker publicou trabalho comunicando uma forma de mucinose cutânea que não havia sido antes registrada. Descreveu-a como “lesões papulosas arredondadas, infiltradas, que logo se tornavam lesões tuberosas, disseminadas: na evolução, se tornavam extensas infiltrações pseudoedematosas”. ...