نتایج جستجو برای: mri contrast agents

تعداد نتایج: 820278  

Journal: :Proceedings of the National Academy of Sciences 2014

Journal: :Magnetic resonance in medicine 2008
Yi Feng Eun-Kee Jeong Aaron M Mohs Lyska Emerson Zheng-Rong Lu

The efficacy of polydisulfide-based biodegradable macromolecular contrast agents for characterizing tumor angiogenesis was investigated in a mouse model using dynamic contrast-enhanced MRI (DCE-MRI). Biodegradable macromolecular MRI contrast agents, gadopentetate dimeglumine (Gd-DTPA) cystamine copolymers (GDCC), and Gd-DTPA cystine copolymers (GDCP), with molecular weights of 20 and 70 kDa wer...

2012
Bernard C. te Boekhorst Geralda A. van Tilborg Gustav J. Strijkers Klaas Nicolay

Inflammatory activity in atherosclerotic plaque is a risk factor for plaque rupture and atherothrombosis and may direct interventional therapy. Inflammatory activity can be evaluated at the (sub)cellular level using in vivo molecular MRI. This paper reviews recent progress in contrast-enhanced molecular MRI to visualize atherosclerotic plaque inflammation. Various MRI contrast agents, among oth...

Bahareh Malekafzali Saeed Pirozi Vahid R Yassaee

Nephrogenic systemic fibrosis (NSF), previously known as nephrogenic fibrosing dermopathy, is an emerging systemic fibrosing disorder that develops in the setting of renal insufficiency. Nephrogenic fibrosing dermopathy (NFD) is a fibrosing condition of the skin which shows an increased number of dendritic cells, fibroblasts and thickened collagen fibers resembling scleromyxedema. It is charact...

Journal: :International Journal of Nanomedicine 2006
Zheng-Rong Lu Aaron M Mohs Yuda Zong Yi Feng

Macromolecular gadolinium (Gd)(III) complexes have a prolonged blood circulation time and can preferentially accumulate in solid tumors, depending on the tumor blood vessel hyperpermeability, resulting in superior contrast enhancement in magnetic resonance (MR) cardiovascular imaging and cancer imaging as shown in animal models. Unfortunately, safety concerns related to these agents' slow elimi...

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