Background Patients with angina without obstructive coronary artery disease are increasingly recognized and microvascular disease (MVD) is thought to play a significant role. An abnormal myocardial perfusion reserve (MPR) by positron emission tomography is predictive of increased cardiovascular events, particularly in women, diabetics, and those with metabolic syndrome. We hypothesized that MPR...

This paper proposes a maximum penetration ranking based approach for siting of Distributed Generators (DG) in a radial distribution system. In this method, the system buses are ranked based on the maximum power that can be injected at each system bus without causing voltage violations. This ranking is called as Maximum Penetration Ranking (MPR) and the buses of laterals with highest MPR are sel...

Multipoint relays have been introduced in the proactive protocol OLSR in order to optimize the flooding overhead of control traffic. In this paper we show that multipoint relaying can be used as well in reactive protocols in order to save overhead in route discovery. To this end we specify a very simple reactive protocol called MPRDV (Multipoint Relay Distance Vector protocol). In MPRDV route r...

A series of recent studies have suggested that endocytosis of the mannose-6-phosphate receptor (MPR)* might play a critical role in delivering the death signal to cells targeted for destruction by the immune system (for review see Barry and Bleackley, 2002). These studies have raised a number of controversial issues regarding the trafficking of proteins from the plasma membrane of the target ce...

PageRank has been widely used to measure the authority or the influence of a user in social networks. However, conventional PageRank only makes use of edge-based relations, ignoring higher-order structures captured by motifs, subgraphs consisting of a small number of nodes in complex networks. In this paper, we propose a novel framework, motif-based PageRank (MPR), to incorporate higher-order s...

The random access protocols with multi packet reception (MPR), which include both slotted-Aloha and slotted τ-persistent CSMA protocols. For both protocols, each node makes a transmission attempt in a slot with a given probability. The transmission channel is divided into equal slot using slottedAloha, then CSMA is used to check whether the channel is idle or not. CSMA is used to avoid collisio...

As a result of the recent advances in physical (PHY) layer communication techniques, it is possible to receive multiple packets at the receiver concurrently. This capability of a receiver to decode multiple simultaneous transmissions is known as multipacket reception (MPR). In this paper, we propose a simple Medium Access Control (MAC) protocol for an MPR wireless channel, where we modify the b...

Mannose 6-phosphate receptors (MPRs) transport newly synthesized lysosomal hydrolases from the Golgi to prelysosomes and then return to the Golgi for another round of transport. We have identified a 47 kDa protein (TIP47) that binds selectively to the cytoplasmic domains of cation-independent and cation-dependent MPRs. TIP47 is present in cytosol and on endosomes and is required for MPR transpo...

Glycoprotein B (gB) is a key component of the complex herpesvirus fusion machinery. We studied membrane interaction of two gB ectodomain forms and present an electron cryotomography structure of the gB-bilayer complex. The two forms differed in presence or absence of the membrane proximal region (MPR) but showed an overall similar trimeric shape. The presence of the MPR impeded interaction with...

Autophagy attenuates the efficacy of conventional chemotherapy but its effects on immunotherapy have been little studied. Here, we report that chemotherapy renders tumor cells more susceptible to lysis by CTL in vivo. Moreover, bystander tumor cells that did not express antigen were killed by CTL. This effect was mediated by transient but dramatic upregulation of the mannose-6-phosphate recepto...