نتایج جستجو برای: mpk

تعداد نتایج: 187  

ژورنال: پژوهش های زعفران 2019

تنش‌های محیطی مهمترین عامل کاهش دهنده عملکرد محصولات کشاورزی در سطح جهان هستند. تنش خشکی یکی از عوامل محدود کننده تولید گیاهان زراعی در سراسر جهان است.برای کاهش اثر تنش های محیطی، یافتن ژنوتیپ‌هایی که دارای ژن‌ها و صفات مطلوبی در این زمینه باشند، مهم است. بدین منظور یکی از مهم‌ترین اهداف تحقیقاتی، درک مکانیسم‌های مولکولی مرتبط با مقاومت به خشکی در گیاهان می‌باشد. با پیشرفت‌های اخیر در زمینه ژنت...

2007
Guy Kortsarz Vahab Mirrokni Zeev Nutov Elena Tsanko

Given a graph with costs on the edges, the power of a node is the maximum cost of an edge leaving it, and the power of the graph is the sum of the powers of its nodes. Motivated by applications in wireless networks, we consider several network design problems under the power minimization criteria. Given a graph G = (V, E) with costs on the edges and requirements r(v) for each v ∈ V , the Min-Po...

2012
Liwen Zhang Timothy McCabe Jon H. Condra Yan G. Ni Laurence B. Peterson Weirong Wang Alison M. Strack Fubao Wang Shilpa Pandit Holly Hammond Dana Wood Dale Lewis Ray Rosa Vivienne Mendoza Anne Marie Cumiskey Douglas G. Johns Barbara C. Hansen Xun Shen Neil Geoghagen Kristian Jensen Lei Zhu Karol Wietecha Douglas Wisniewski Lingyi Huang Jing Zhang Zhao Robin Ernst Richard Hampton Peter Haytko Frances Ansbro Shannon Chilewski Jayne Chin Lyndon J. Mitnaul Andrea Pellacani Carl P. Sparrow Zhiqiang An William Strohl Brian Hubbard Andrew S. Plump Daniel Blom Ayesha Sitlani

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a promising therapeutic target for treating coronary heart disease. We report a novel antibody 1B20 that binds to PCSK9 with sub-nanomolar affinity and antagonizes PCSK9 function in-vitro. In CETP/LDLR-hemi mice two successive doses of 1B20, administered 14 days apart at 3 or 10 mpk, induced dose dependent reductions in LDL-cholesterol (≥...

Journal: :Genes & development 1995
Y Wu M Han K L Guan

Activated Ras initiates a cascade of sequential phosphorylation events, including the protein kinases Raf, MEK, and MAP kinase. The Let-60 Ras-mediated signal transduction pathway controls vulval induction in Caenorhabditis elegans. Both Lin-45 Raf and Sur-1 MAP kinase have been determined to be essential factors during vulval induction; however, the C. elegans mek gene has not been identified....

Journal: :Eukaryotic cell 2005
Damian J Krysan Elizabeth L Ting Claudia Abeijon Lee Kroos Robert S Fuller

The yeast cell wall is a crucial extracellular organelle that protects the cell from lysis during environmental stress and morphogenesis. Here, we demonstrate that the yapsin family of five glycosylphosphatidylinositol-linked aspartyl proteases is required for cell wall integrity in Saccharomyces cerevisiae. Yapsin null mutants show hypersensitivity to cell wall perturbation, and both the yps1D...

2017
Durdica Marosevic Gabriele Margos Reinhard Wallich Andreas Wieser Andreas Sing Volker Fingerle

BACKGROUND Borrelia recurrentis is the causative agent of louse-borne relapsing fever, endemic to the Horn of Africa. New attention was raised in Europe, with the highest number of cases (n = 45) reported among migrants in 2015 in Germany and sporadically from other European countries. So far only one genome was sequenced, hindering the development of specific molecular diagnostic and typing to...

Journal: :Plant physiology 2015
Fei Wang Yan Yang Zhe Wang Jie Zhou Baofang Fan Zhixiang Chen

Multivesicular bodies (MVBs) are unique endosomes containing vesicles in the lumen and play critical roles in many cellular processes. We have recently shown that Arabidopsis (Arabidopsis thaliana) Lyst-Interacting Protein5 (LIP5), a positive regulator of the Suppressor of K(+) Transport Growth Defect1 (SKD1) AAA ATPase in MVB biogenesis, is a critical target of the mitogen-activated protein ki...

احمد اخیانی سید امیر عطاردی سیدحسن موسوی فضل,

به­منظور بررسی اثر آب آبیاری و کود پتاسیم بر عملکرد و اجزای عملکرد سورگوم علوفه­ای، پژوهشی در مرکز تحقیقات و آموزش کشاورزی استان سمنان(شاهرود) در سال 1393 انجام شد. فاکتورهای این پژوهش شامل آب آبیاری در سه سطح (50، 75 و 100 درصد نیاز آبی)، کود پتاسیم در سه سطح (صفر، 50 و 100 درصد نیاز کودی) و ارقام سورگوم علوفه­ای (پگاه، کرج و اسپیدفید) بودند. آب آبیاری با استفاده از داده­های هواشناسی منطقه به ...

Journal: :Eur. J. Comb. 2008
Victor J. W. Guo

We give a new proof of a theorem of Mansour and Sun by using number theory and Rothe’s identity. It is well-known that the number of ways of choosing k points, no two consecutive, from a collection of n points arranged on a cycle is n n−k ( n−k k ) (see [11, Lemma 2.3.4]). A generalization of this result was obtained by Kaplansky [5], who proved that the number of k-subsets {x1, . . . , xk} of ...

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