oral lichen planus is a chronic inflammatory immune-mediated disease. icam-1 and vcam-1 are vascular adhesion molecules that their receptors are located on endothelial cells and leukocytes. the aim of this study is the immunohistochemical evaluation of vcam1 and icam1 in oral lichen planus and to compare these two markers with normal mucosa for evaluation of angiogenesis. this descriptive-analy...

in current study, a few sheep cystic livers and lungs were obtained from mashhad slaughter house and protoscolex were separated aseptically. thirty 6-week-old swiss mice were divided into 5 groups and two thousands of live protoscolices were inoculated intrapritoaneally in each mouse. in group 1 and 2 (prophylactic groups), mice were given 150 mg/kg of oral albendazole and mebendazole for 10 da...

the effects of adenosine,5-n-ethylcarbox-amidoadenosine (neca), 2-chloroadenosine (2-ca), n6-phenyiisopropyladenos'tne (l-pia and d-pia) and n6 -cyclohexyladenos'tne (cha) were examined on the mouse isolated vas deferens. all the compounds in a concentration-dependent manner inhibited electrically induced contrac¬tions. ic of adenosine and its analogues were 13.68 ± 5.97 for ado, 0.736 ± 0.087 ...

background: after improvements in various cancer treatments, life expectancy has been raised, but success in treatment causes loss of fertility in many of the survived young men. cryopreservation of immature testicular tissues or cells introduced as the only way to preserve fertility. however, freezing has some harmful effects. melatonin, a pineal gland hormone, has receptors in reproductive sy...

background: lead is an industrial heavy metal that can decrease sperm motility. objective: the aim was to investigate the protective effects of calcium against lead on motility of spermatozoa. materials and methods: in total 40 adult male swiss white mice were randomly divided into 5 groups (control, lead of 1st wk, lead of 2nd wk, lead/calcium of 1st wk and lead/calcium of 2nd wk). the lead gr...

Glyburide (Gly) could inhibit NLRP3 inflammasome, as well be treated with Type 2 diabetes a common medication. Despite more and studies show that Gly influence cancer risk tumor growth, it remains unclear about the effect of in lung tumorigenesis. To evaluate whether inhibited tumorigenesis explore possible mechanisms, benzo(a)pyrene [B(a)p] plus lipopolysaccharide (LPS)-induced non-diabetes mi...

background: the ability of polyclonal antibodies to react with many epitopes of an antigen makes them valuable reagents in research and diagnosis. the aim of this study was purification of mouse igg2a and production of polyclonal antibody against purified mouse igg2a subclass. materials and methods: mouse igg2a was purified by proa affinity. verification method of the purified antibody was sds-...