Background: Flat urothelial lesions comprise a spectrum of morphologic changes ranging from reactive atypia to carcinoma in situ (CIS). Urothelial dysplasia and CIS are associated with the recurrence and progression of urothelial carcinoma. Distinguishing CIS and dysplasia from reactive atypia based on histolopathogical features alone is often difficult. Using different immunohistochemical mark...

I N SPITE of the rarity of eosinophilic leukemia, many investigators have reported a number of morphologic alterations of the eos nophils present in the blood and/or bone marrow of patients with eosinophilic leukemia.6’1 ‘ 13.1 6, 18, 19,21 ,24,26,293 I ,34,36,39,40,42,45,4753 The cytologic alterations have included a sparcity of eosinophilic granulation in the mature eosinophils, asynchronous ...

2. The palcogeography of the eastern Gulf Coast during Jacksonian (Late Eocene) limes was reconstructed by a combination taxonomic-morphologic method. For Tertiary faunules some of the precision lost by using taxonomic data alone, by the change from specific to generic level, is restored by adding morphologic data. This treatment of Jacksonian faunules is an elaboration of one introduced by L. ...

A useful classification of acute leukemia must be reproducible, must impart understanding of leukemogenesis and clinical behavior, and (most importantly) be clinically relevant, which makes such a classification indispensable for designing and comparing clinical trials. Classification systems by their very nature may influence the design of treatment regimens and may even bias investigations of...

background: flat urothelial lesions comprise a spectrum of morphologic changes ranging from reactive atypia to carcinoma in situ (cis). urothelial dysplasia and cis are associated with the recurrence and progression of urothelial carcinoma. distinguishing cis and dysplasia from reactive atypia based on histolopathogical features alone is often difficult. using different immunohistochemical mark...

background: flat urothelial lesions comprise a spectrum of morphologic changes ranging from reactive atypia to carcinoma in situ (cis). urothelial dysplasia and cis are associated with the recurrence and progression of urothelial carcinoma. distinguishing cis and dysplasia from reactive atypia based on histolopathogical features alone is often difficult. using different immunohistochemical mark...

I N SPITE of the rarity of eosinophilic leukemia, many investigators have reported a number of morphologic alterations of the eos nophils present in the blood and/or bone marrow of patients with eosinophilic leukemia.6’1 ‘ 13.1 6, 18, 19,21 ,24,26,293 I ,34,36,39,40,42,45,4753 The cytologic alterations have included a sparcity of eosinophilic granulation in the mature eosinophils, asynchronous ...

Apocrine carcinoma of the breast is a rare, special type of breast carcinoma showing distinct morphologic, immunohistochemical and molecular genetic features. Apocrine epithelium has a characteristic steroid receptor profile that is estrogen receptor and progesterone receptor negative and androgen receptor positive. This combination of morphologic and immunohistochemical characteristics is esse...

Granulocytic fragments have been described in the peripheral blood of patients with sepsis and the systemic inflammatory response syndrome (SIRS). Although initially proposed as a morphologic clue for distinguishing the leukoerythroblastosis of sepsis from that of myelophthisis or marrow replacement by tumor, granulocyte-derived fragments may be part of a spectrum of cellular fragmentation asso...