objective(s): the effect of the extract of crocus sativus and its constituent, safranal on inflammatory markers in sensitized guinea pigs was examined.   materials and methods: ovalbumin (oa) sensitized guinea pigs were given drinking water alone (group s), or drinking water containing three concentrations of safranal, three concentrations of extract and one concentration of dexamethasone, (n=6...

Repeated administration of abused drugs sensitizes their stimulant effects and results in a drug-paired environment eliciting conditioned activity. We tested whether food induces similar effects. Food-deprived male mice were given novel food during 30 min tests in a runway (FR group) that measured locomotor activity. Whereas the activity of this group increased with repeated testing, that of a ...