. Demonstrate an understanding of the natural history and manifestations of reflux disease . Evaluate the role of diagnostic testing such as endoscopy, esophageal manometry, ambulatory pH monitoring, and impedance-pH monitoring in the management of patients with gastroesophageal reflux disease . Evaluate the options for treatment of patients with complicated and uncomplicated reflux disease.

OBJECTIVES To compare the aryepiglottic (AE) length in pediatric patients who have severe laryngomalacia (SL) and are undergoing aryepiglottoplasty with the AE length of a convenience sample of control patients without laryngomalacia. DESIGN Prospective case-control study. SETTING A tertiary-care pediatric hospital. RESULTS The mean AE fold length-glottic length ratio for patients with SL...

Obesity, gastroesophageal reflux, and smoking have repeatedly been shown to be important and independent risk factors for adenocarcinoma of the esophagus (EAC) and of the gastroesophageal junction (GEJAC). There have been few attempts, however, to quantify the proportion of disease associated with these potentially modifiable factors. The authors have estimated the population attributable fract...

Dentists are often the first healthcare line that can – diagnose certain systemic diseases through their oral manifestations. One of such diseases is the gastroesophageal reflux disease (GERD) which may be recognised through its extraesophageal manifestation in the form of dental erosions (Howeden, 1971; Myllarniemi & Saario, 1985; Jarvinen et al., 1988; Bartlett & Smith.1996; Lazarchik &Filler...

BACKGROUND Laparoscopic fundoplication has become the criterion standard for the surgical treatment of gastroesophageal reflux disease. Recently, several patients were referred with recurrent symptoms of gastroesophageal reflux disease or severe dysphagia following previous antireflux surgery for possible laparoscopic reoperation. HYPOTHESIS To determine the safety and efficacy of this proced...

Gastroesophageal reflux disease (GERD) and GERD-related symptoms are common, and affect 25% to 30% of the general population. Upper gastrointestinal endoscopy of the esophagus has been the most widely used modality for the diagnosis and grading of reflux disease. Endoscopic imaging today has evolved beyond the confines of routine white light endoscopy (WLE) to advanced optical imaging with a pr...

Obesity, gastroesophageal reflux, and smoking have repeatedly been shown to be important and independent risk factors for adenocarcinoma of the esophagus (EAC) and of the gastroesophageal junction (GEJAC). There have been few attempts, however, to quantify the proportion of disease associated with these potentially modifiable factors. The authors have estimated the population attributable fract...

Although gastroesophageal reflux disease is not as common in Asia as in western countries, the prevalence has increased substantially during the past decade. Gastroesophageal reflux disease is associated with considerable reductions in subjective well-being and work productivity, as well as increased healthcare use. Proton pump inhibitors (PPIs) are currently the most effective treatment for ga...