Gd4O2S:Yb:Tm rare-earth upconversion phosphors have been utilised to monitor the redox behaviour of flavin mononucleotide and report on the turnover of a flavo-protein, (pentaerythritol tetranitrate reductase). The presence of two bands separated by over 300 nm in the UCP emission spectra allows ratiometric signalling of these processes with high sensitivity.

The biosynthetic pathway of diphosphopyridine nucleotide has been formulated through a study of yeast autolysates, erythrocytes, and liver homogenates. Two such pathways have been described by these procedures. Each system ultimately utilizes the enzyme diphosphopyridine nucleotide pyrophosphorylase. In the first pathway, the enzyme produces diphosphopyridine nucleotide directly by coupling ade...

Catalytic hydrogenation of the appropriate pyridine nucleotide coenzymes and their derivatives over palladium supported on barium carbonate in aqueous solution has yielded the following representatives of two novel series of coenzyme analogues: tetrahydronicotinamide adenine dinucleotide, tetrahydronicotinamide mononucleotide, 3-acetyltetrahydropyridine adenine dinucleotide, hexahydronicotinami...

Submit Manuscript | http://medcraveonline.com Abbrevations: PBEF: Pre-B cell colony Enhancing Factor; NAD: Nicotinamide Adenine Dinucleotide; Sir2: Silent information regulator 2; NMN: Nicotinamide Mononucleotide; GLP-1: Glucagon Like Peptide-1; SAT: Subcutaneous Adipose Tissue; VAT: Visceral Adipose Tissue; FSIGT: Frequently Sampled Intravenous Glucose Tolerance; IMCL: Intramyocellular Lipid; ...

This contribution highlights correlation between the surface concentration of a chemisorbed organophosphorous probe (flavin mononucleotide) and the relative hydroxyl surface coverage of nanostructured ITO electrodes, which can be tuned during post-deposition reductive annealing. The resulting modified electrodes are very stable in aqueous solution, highly hydrophilic and fully-accessible to the...

The luminescence signal of luxAB-encoded bacterial luciferase strongly depends on the metabolic state of the host cell, which restricts the use of this reporter system to metabolically active bacteria. Here we show that in stationary-phase cells of Lactococcus lactis, detection of luciferase is significantly improved by the addition of riboflavin or flavin mononucleotide to whole-cell assay sys...

The catabolic pathway for flavodoxin has yet to be clarified for any bacterial species. In this study, we found that the flavin mononucleotide in the flavodoxin of Helicobacter pylori is degraded to riboflavin via the phosphomonoesterase activity of class C acid phosphatase. The result is a conversion of holoflavodoxin to apoflavodoxin.