To evaluate the transport properties of the alveolar epithelium, we instilled hetastarch (Het; 6%, 10 ml, 1 - 1 x 10(4) kDa) into the trachea of isolated rat lungs and then measured the molecular distribution of Het that entered the lung perfusate from the air space over 6 h. Het transport was driven by either diffusion or an oncotic gradient. Perfusate Het had a unique, bimodal molecular weigh...

An integrated picture of the distribution of functional groups should be provided as a function of molecular size within residual kraft lignins. With this goal we developed a reliable and reproducible method for determination of the molecular weight and molecular weight distribution of residual kraft lignins (RKLs) over the whole delignification range. In general, our data indicate that for rel...

in atom transfer radical polymerization (atrp) of methyl acrylate (ma) with polyvinyl acetate macroinitiator in bulk at 90°c the plots of ln [m]0/[m] increased linearly with reaction time. the apparent propagation rate constant (kp app) of the reaction was obtained from the linear curve and used to calculate the free macroradical concentration ([r°]) in polymerization medium. the [r°] and also ...

radiation degradation of chitosan is one of the most important methods to prepare antibacterial oligochitosans. in this study, the effect of solvent on the reduction of degradation dose and enhancement of the antibacterialactivity of chitosan against pectobacterium carotovorum (pc) has been considered.gamma radiation degradation was applied to chitosan as solid and aqueous solution at dose rang...

background: this study was designed to examine a unique and low dose use of intravenous enoxaparin in elective percutaneous coronary intervention (pci) that would be applicable to an unselected population regardless of age, weight, and renal function. there is limited experience in anticoagulation using intravenous low-molecular-weight heparin in pci. methods: a total of 100 consecutive patient...

To evaluate the effect of diffusion on the pulmonary extravascular water volume determined from indicator dilution studies, simultaneous comparisons of the pulmonary extravascular distribution volumes of tritiated water (THO) and of three lipid soluble substances with higher molecular weights were made. In 21 studies on pentobarbital-anesthetized dogs, the distribution volume of antipyrine (AP)...

Antidepressants, especially amitriptyline, are among themost frequent drug classes involved in intoxications. Despite its small molecular weight, amitriptyline is not considered to be eliminated by extracorporeal treatmentmethods due to its high protein binding and large volume of distribution. New high cut-off dialysers have so far not been used for removal of amitriptyline. We report two case...

Antidepressants, especially amitriptyline, are among the most frequent drug classes involved in intoxications. Despite its small molecular weight, amitriptyline is not considered to be eliminated by extracorporeal treatment methods due to its high protein binding and large volume of distribution. New high cut-off dialysers have so far not been used for removal of amitriptyline. We report two ca...