The ability to form associations between a multitude of events is the hallmark of episodic memory. Computational models have espoused the importance of the hippocampus as convergence zone, binding different aspects of an episode into a coherent representation, by integrating information from multiple brain regions. However, evidence for this long-held hypothesis is limited, since previous work ...

The authors argue that the concept of anatomical canon is not just an arbitrary standard beauty but indispensable mnemonic tool for artist. further most relevant when adapted to a specific artistic process and tools, in particular must be updated requirements digital tools 3D modeling. A proposal such discussed, as well its synthesis from primitives applications.

Some superior memorists demonstrated exceptional memory for reciting a large body of information. The underlying neural correlates, however, are seldom addressed. C.L., the current holder of Guinness World Record for reciting 67,890 digits in π, participated in this functional magnetic resonance imaging (fMRI) study. Thirteen participants without any mnemonics training were included as controls...

Recent models of episodic memory propose a division of labor among medial temporal lobe cortices comprising the parahippocampal gyrus. Specifically, perirhinal and lateral entorhinal cortices are thought to comprise an object/item information pathway, whereas parahippocampal and medial entorhinal cortices are thought to comprise a spatial/contextual information pathway. Although several studies...

T lifetime prevalence of generalized anxiety disorder (GAD) is between 6% and 10% in the general population; more women than men are aff ected.1 Studies of anxiety disorders in primary care populations have shown that up to 18% of patients suff er from any anxiety disorder, and 7% of patients have GAD. A study of 6370 primary care patients found that 33% of patients reported anxiety symptoms, b...

In this essay, I borrow the idea of universal precautions from infection control and suggest that family physicians use a set of considerations, based on the mnemonic UNIVERSAL, to nurture cultural humility, enter a metaphoric "space-in-between" in cross-cultural encounters, and foster global fluency. These UNIVERSAL considerations I base on my experiences in global family medicine, attending t...

Accessing stored knowledge is a fundamental function of the cognitive and neural architectures of memory. Here, the authors review evidence from cognitive-behavioral paradigms, neuropsychological studies of patients with focal neural insult, and functional brain imaging concerning the mechanisms underlying retrieval of semantic knowledge and their association with prefrontal cortex. First, the ...

Most perceptual decisions require comparisons between current input and an internal template. Classic studies propose that templates are encoded in sustained activity of sensory neurons. However, stimulus encoding is itself dynamic, tracing a complex trajectory through activity space. Which part of this trajectory is pre-activated to reflect the template? Here we recorded magneto- and electroen...