Background: Think of all the different ways we treat warts and you have an overview of the stark fact that nothing works all that well. One common technique used especially in primary care is immunotherapy with Candida antigen. There have been literature reports of success also with mumps, Trichophyton, and tuberculin vaccines. Objective: To test the effectiveness of the use of measles/mumps/ru...

A suggested association between certain childhood vaccines and autism has been one of the most contentious vaccine safety controversies in recent years. Despite compelling scientific evidence against a causal association, many parents and parent advocacy groups continue to suspect that vaccines, particularly measles-mumps-rubella (MMR) vaccine and thimerosal-containing vaccines (TCVs), can caus...

Here we report horizontal symptomatic transmission of the Leningrad-Zagreb (L-Zagreb) mumps vaccine virus. Children who were the source of transmission had been vaccinated with the MMR vaccine (Serum Institute of India) contained L-Zagreb mumps virus. This is the first report of horizontal symptomatic transmission of this vaccine. The etiology of all seven contact cases was confirmed by epidemi...

We adapt the self-controlled case series method for long-term surveillance of vaccine safety using cumulative sum (CUSUM) charts. The CUSUM surveillance method we propose is applicable for detecting associations that arise in a short pre-determined risk period following vaccination. The performance of the case series CUSUM is investigated through simulations. We illustrate the method using retr...

Immunization programs have often been impeded by vaccine scares, as evidenced by the measles-mumps-rubella (MMR) autism vaccine scare in Britain. A "free rider" effect may be partly responsible: vaccine-generated herd immunity can reduce disease incidence to such low levels that real or imagined vaccine risks appear large in comparison, causing individuals to cease vaccinating. This implies a f...

Measles-mumps-rubella (MMR) vaccines containing the Urabe strain of mumps were withdrawn in the United Kingdom in 1992 following demonstration of an increased risk of aseptic meningitis 15-35 days after vaccination. Following introduction of a replacement MMR vaccine (Priorix; GlaxoSmithKline, London, United Kingdom) in 1998, active surveillance of aseptic meningitis and convulsion was establis...

During March to May 2006 the highest incidence of measles in New South Wales since 1998 provided an opportunity to estimate the effectiveness of the measles-mumps-rubella (MMR) vaccination program in preventing childhood measles, and describe any differences in clinical presentation between vaccinated and unvaccinated children. We reviewed records of all 33 notified cases of measles in children...

Background. Parents and physicians are understandably concerned about the causes and treatment of autism, a devastating disease that affects the entire family. Although much has been learned about autism, there are many gaps in our knowledge about what causes the disorder and how it can be prevented. Autistic symptoms occur along a spectrum, often referred to as autistic spectrum disorder (ASD)...

Measles and mumps outbreaks in the United States have laimed numerous headlines over the past six months. The 397 easles cases in the U.S. from January 1 to June 6, 2014 have urpassed the highest annual totals since the 2000 declaration of easles elimination in the U.S. [1]. Mumps outbreaks have made heir marks across college campuses in Ohio and New York. What imilarities have there been in th...