background and objectives: lipoprotein-a potentially represents a useful tool for risk stratification in cardiovascular accidents.  the aim of this study was to evaluate the atorvastatin effect on serum lipid profile & lipoprotein a. material & methods: in 2009, 405 patients with acute coronary syndrome randomly were divided into 2 groups, taking 20 & 40 mg atorvastatin daily for 3...

introduction: congenital anomalies are a common cause of disability and mortality in newborns and their treatments involves high costs for the society. this study aimed to investigate the prevalence of congenital anomalies and their causes. materials and methods: this research was a descriptive-analytical study and the population included all the newborns in hospitals of the city of ilam in 201...

coincidence of autoimmune diseases such as immune thrombocytopenic purpura (itp) with  immunodeficiencies has  been  reported  previously in  patients  who  suffered  from primary antibody deficiency (pad). but there is no original study on immunological profiles of itp patients to find out their probable immune deficiency. in this case-control study, itp patients’ humoral immunity was investig...

background: the use of organophosphates (ops) in developing countries is rising in large quantities and non-secure methods. this problem not only causes acute poisoning but also may lead to chronic diseases such as polyneuropathy. in iran, 60% of pesticides are organophosphate compounds that may lead to delayed polyneuropathy. objectives: the purpose of the current study was to evaluate delayed...

purpose: to evaluate the prevalence and risk factors of dry eye in the patients referred to an eye clinic in birjand, iran. methods: this cross sectional descriptive-analytical study consisted of 600 patients who were referred to the eye clinic of birjand, iran between september 2010 and september 2011. they were given a simple questionnaire about the risk factors of dry eye including the demog...

Considerable evidence suggests that mitochondrial dysfunction contributes to the toxicity of uranyl acetate (UA), a soluble salt of depleted uranium (DU). We examined the ability of the two antioxidants, beta-glucan and butylated hydroxyl toluene (BHT), to prevent UA-induced mitochondrial dysfunction using rat-isolated kidney mitochondria. Beta-glucan (150 nM) and BHT (20 nM) attenuated UA-indu...

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based on the similarity of prokaryotic dna to that of mitochondrial dna, a rapid and efficient method for dna purification from mitochondrial extracts obtained from different sources, was carried out based on the modification method described by marmur (1983) which resulted in a high degree of purity (a260/a280=2). in addition we have applied the same technique for the first time to purify the ...

OBJECTIVE To verify the phenotype to genotype correlations of mitochondrial DNA (mtDNA) related disorders in an atypical maternally inherited encephalomyopathy. METHODS Neuroradiological, morphological, biochemical, and molecular genetic analyses were performed on the affected members of a pedigree harbouring the heteroplasmic A to G transition at nucleotide 3243 of the mitochondrial tRNALeu(...