introduction: multiple sclerosis is a chronic inflammatory disease of central nervous system. the etiology of ms is slightly known, but genetic and environmental factors are reported. vitamin d regulates gene expression and affects target cell functions. the aim of this study was to investigate the expression variation of il-2 and il-4 genes under vitamin d supplementation in patients with mult...

background and purpose: multiple sclerosis (ms) is believed to be an immune-mediated disorder that develops from an interaction of the individual's genetic and as yet unidentified environmental causes. the prevalence of auto-antibodies in multiple sclerosis patients and their clinical associations vary in various studies. the aim of this study was to determine serum auto antibodies in multiple ...

Background: Since in multiple sclerosis (MS), changes in speech and voice quality often precede other signs and symptoms; early diagnosis of these changes is necessary. In this study, an acoustic examination of phonation subsystem was performed. Due to the progressive nature of multiple sclerosis, the aim of this study was to examine the correlation between acoustic parameters ...

Background: Multiple sclerosis is one of the most debilitating diseases of the central nervous system, which has chronic process. Clinical manifestations of this disease can also affect their daily activities and, as a result, reduce the quality of life in these people. Thus, considering the importance of quality of life in patients with multiple sclerosis, the present study examines the relati...

Introduction: Recent studies point to the clinical and research efficacy of saliva as a respected diagnostic aid for observing Multiple Sclerosis. The objectives of this Hypothesis are to identify novel biomarkers recognized to Multiple Sclerosis in early stage in saliva and to determine if the levels of these markers correlate with level of these Cerebrospinal fluid and blood assays and urine ...

background: disability is the most important determinants of disease course, treatment and rehabilitation outcomes and consequently the quality of life in patients with multiple sclerosis. the aim of the present study was to determine the relationship of disability and quality of life in multiple sclerosis patients.   methods: this cross-sectional study was performed on 325 patients referred to...

introduction: multiple sclerosis is a progressive neurological disease is most common in young adults. this disease has created many problems for patients and it leads to disability and dependence in life. clinical findings indicate that mental stress of everyday life events gradually work different body systems including the immune system is affected and can weaken it. various factors can modu...