نتایج جستجو برای: mir31

تعداد نتایج: 174  

2015
Pak Cheung Ng Kathy Yuen Yee Chan Kam Tong Leung Yuk Him Tam Terence Ping Yuen Ma Hugh Simon Lam Hon Ming Cheung Kim Hung Lee Ka Fai To Karen Li Josef Neu

BACKGROUND Necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP) are acute intestinal conditions which could result in mortality and severe morbidity in preterm infants. Our objective was to identify dysregulated micro-RNAs (miRNAs) in small bowel tissues of NEC and SIP, and their possible roles in disease pathophysiology. METHODS We performed differential miRNA arrays ...

2017
Itziar Eseberri Arrate Lasa Jonatan Miranda Ana Gracia Maria P Portillo

OBJECTIVE Scientific research is constantly striving to find molecules which are effective against excessive body fat and its associated complications. Taking into account the beneficial effects that resveratrol exerts on other pathologies through miRNA, the aim of the present work was to analyze the possible involvement of miRNAs in the regulation of adipogenic transcription factors peroxisome...

Journal: :European heart journal 2014
Thomas F Lüscher

The current issue of the European Heart Journal focuses on a novel area of research, i.e. the function of microribonucloidacids (miRNAs). miRNAs are short, usually around 22-nucleotide-long non-coding RNAs involved in the regulation of gene expression (Figure 1). They guide ribonucleoprotein complexes that induce translational repression or messenger RNA degradation to targeted messenger RNAs. ...

2013
Pei-Chun Lin Ya-Lin Chiu Samprit Banerjee Kyung Park Juan Miguel Mosquera Eugenia Giannopoulou Pedro Alves Ashutosh K. Tewari Mark B. Gerstein Himisha Beltran Ari M. Melnick Olivier Elemento Francesca Demichelis Mark A. Rubin

Androgen receptor signaling plays a critical role in prostate cancer pathogenesis. Yet, the regulation of androgen receptor signaling remains elusive. Even with stringent androgen deprivation therapy, androgen receptor signaling persists. Here, our data suggest that there is a complex interaction between the expression of the tumor suppressor miRNA, miR-31, and androgen receptor signaling. We e...

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