UNLABELLED It is not currently possible to predict the probability of whether a woman with a chlamydial genital infection will develop pelvic inflammatory disease (PID). To determine if specific biomarkers may be associated with distinct chlamydial pathotypes, we utilized two Chlamydia muridarum variants (C. muridarum Var001 [CmVar001] and CmVar004) that differ in their abilities to elicit uppe...

Micro structure is the microscopic surface topography of an implant. In simple terms, is it smooth or is it rough. The rougher the surface, the better. A roughened surface is directly associated with higher implant survival rates (Figure 1) [2]. Micro structure has a direct effect on the osseointegrative process and therefore most important in the long term stability of an implant after healing...

Model selection is commonly based on some variation of the BIC or minimum message length criteria, such as MML and MDL. In either case the criterion is split into two terms: one for the model (data code length/model complexity) and one for the data given the model (message length/data likelihood). For problems such as change detection, unsupervised segmentation or data clustering it is common p...

Mutations in the BRCA1/BRCA2 genes account for varying proportions of breast cancer families studied, and demonstrate considerable variation in mutational spectra coincident with ethnic and geographical diversity. This work aimed to identify mutations in BRCA1 and BRCA2 genes to explore the existence of population-specific recurrent or founder mutations, in Tunisian breast cancer families. We h...

The model selection criteria AIC, BIC and Cp have been proposed for estimation of the rank of coefficient matrix in multivariate linear model. In general, it is known that under a large-sample asymptotic framework AIC and Cp is not consistent, but BIC is consistent. However, we note that these criteria have consistency when the number p of the response variables and the sample size n are large ...

Background The nicotine may generate a influence on bone repair and longevity of dental implants. This fact makes studies to improve the surface of the implants are constantly conducted. This study aimed to evaluate the influence of subcutaneous nicotine injection in the osseointegration process on different implant surfaces, through histomorphometric analysis. Material and Methods Therefore,...

OBJECTIVE To evaluate and compare the organization of descending motor pathways to upper extremity muscles among healthy children. METHOD The healthy children were 16 males and 7 females aged 1-19 years (average, 9 years), and eight healthy adults were enrolled as the control group. Transcranial magnetic stimulation was applied to bilateral motor cortices, and motor evoked potentials (MEPs) w...

OBJECTIVES This preliminary investigation aimed to evaluate the potential of contaminated implants to reosseointegrate into pristine sites and, in addition, to assess the potential of osseointegration of new implants in peri-implantitis sockets in a canine model. METHODS All mandibular premolars were bilaterally extracted from two mongrel dogs. Following 12 weeks of healing, two dental implan...

This paper presents a new method of model selection for regression problems using the modulus of continuity. For this purpose, we suggest the prediction risk bounds of regression models using the modulus of continuity which can be interpreted as the complexity of functions. We also present the model selection criterion referred to as the modulus of continuity information criterion (MCIC) which ...

BACKGROUND Automatic stepwise subset selection methods in linear regression often perform poorly, both in terms of variable selection and estimation of coefficients and standard errors, especially when number of independent variables is large and multicollinearity is present. Yet, stepwise algorithms remain the dominant method in medical and epidemiological research. METHODS Performance of st...