Migraine is the sixth most common cause of disability in the world. Preventive migraine treatment is used to reduce frequency, severity and duration of attacks and therefore lightens the burden on the patients' quality of life and reduces disability. Topiramate is one of the preventive migraine treatments of proven efficacy. The mechanism of action underlying the preventive effect of topiramate...

BACKGROUND Many women with migraine experience a change in migraine frequency associated with the menstrual cycle. This study was undertaken to study the effect of vitamin E as a prophylactic agent on women with menstrual migraine. MATERIAL/METHOD During a placebo-controlled double-blinded trial, 72 women with menstrual migraine received placebo (identical in appearance to vitamin E) daily fo...

OBJECTIVE Our objective was to assess the safety, feasibility, and effects of the standardized 8-week mindfulness-based stress reduction (MBSR) course in adults with migraines. BACKGROUND Stress is a well-known trigger for headaches. Research supports the general benefits of mind/body interventions for migraines, but there are few rigorous studies supporting the use of specific standardized i...

Migraine is a recurrent incapacitating neurovascular disorder characterized by attacks of debilitating pain associated with photophobia, phonophobia, nausea and vomiting. Migraine affects a substantial fraction of world population and is a major cause of disability in the work place. Though the pathophysiology of migraine is still unclear three major theories proposed with regard to the mechani...

Migraine is a common primary headache disorder often associated with significant disability. While many individuals are able to limit therapy to acute treatment of attacks, others need medication to reduce the attack frequency and/or severity. Evidence-based guidelines exist regarding indications and goals for migraine preventive treatment. The specific prophylactic approach needs to be individ...

CONCLUSION: MIDAS is suboptimal to describe disability in our patients due to a mean preoperative score of 102, as severe disability is defined as 21+. PSEQ successfully demonstrates extent of disability in this patient population and puts migraine surgery in perspective to other known pain treatments. It further evaluates functional outcome, rather than just improvement in symptoms. This signi...

BACKGROUND Cutaneous allodynia (CA) is a common feature of migraine, which has a complex underlying pathophysiology that is not well understood. In addition to pain, photophobia, phonophobia, osmophobia, nausea, and vomiting, CA can contribute to the overall disability caused by migraine. The presence of CA can be established via a validated questionnaire. Validated questionnaires and other tes...

Abstract Background Allergy immunology specialists frequently encounter with diagnosis of migraine headache; this is a prospective study to assess the ability treatment allergic rhinitis in patients having decrease attacks migraine. Results Between June 2016 and Feb. 2019, 58 suffer from positive symptoms for all patients. CBC differential, nasal smear IgE test assessment disability score, comp...

The aim of this study was to evaluate and define the triggers of the acute migraine attack. Patients rated triggers on a 0-3 scale for the average headache. Demographics, prodrome, aura, headache characteristics, postdrome, medication responsiveness, acute and chronic disability, sleep characteristics and social and personal characteristics were also recorded. One thousand two hundred and seven...