نتایج جستجو برای: microsatellites of dna
تعداد نتایج: 21220038 فیلتر نتایج به سال:
The status of genetic diversity, adaptation to climate change or the identification genes associated with traits interest in livestock populations has been a major concern for scientists last decades. Biotechnology evolved continuously, offering new tools and methodologies analyse genomes species. Biochemical markers protein polymorphisms were used population studies many years ago, but over th...
Simple sequence repeats (SSRs), or microsatellites, have been isolated and characterized from numerous animal and plant species (6,7). These sequences have been shown to be highly polymorphic between individuals within populations or closely related genotypes. This, together with the fact that they can be converted into a simple polymerase chain reaction (PCR)based assay, has led to their wides...
Abstract Island populations may have a higher extinction risk due to reduced genetic diversity and need be managed effectively in order reduce the of biodiversity loss. The Eurasian red squirrels ( Sciurus vulgaris ) south England only survive on three islands (the Isle Wight, Brownsea Furzey islands), with Wight harbouring largest population region. Fourteen microsatellites were used determine...
Microsatellites are short tandem repeats of deoxyribonucleic acid (DNA) sequences which are distributed throughout the genome. Tumors in patients with Lynch syndrome tend to accumulate mutations in microsatellites at a much higher rate than other sequences in the genome resulting in microsatellite instability (MSI). This is due to germline mutations in mismatch repair (MMR) genes. Using small p...
Microsatellites are tandem repeats of simple polymorphic sequences randomly distributed in non-coding regions of DNA. They can be used in cancer genetics and indirect cancer diagnosis and can help unraveling the genetic basis of tumor formation and progression of cancer. Breast cancer is a complex disease in which numerous genetic alterations occur. The knowledge of specific genetic changes and...
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