Microemulsion-based organogels (MBGs) were effectively employed for the immobilization of four commonly used lipases. During the asymmetric hydrolysis of ketoprofen vinyl ester at 30 °C for 24 h, lipase from Rhizomucor miehei and Mucor javanicus immobilized in microemulsion-based organogels (RML MBGs and MJL MBGs) maintained good enantioselectivities (eep were 86.2% and 99.2%, respectively), an...

Topical microemulsion of capsaicin without surfactant was developed in this study. In these systems, the oil phase was benzyl alcohol, and the cosurfactant was propylene glycol and ethanol. The drop-size of the systems was measured by dynamic light scattering method in order to distinguish true solution from microemulsion. The transdermal performance of the microemulsions was evaluated in vitro...

The microstructure of the water rich microemulsion phase of the Cj~E~. water and decane system has been studied using surfactant ~H-NMR relaxation and 'H Fourier transform pulsed gradient spin-echo jFTPGSE) self-diffusion experiments. The surfactant-to-oil ratio is kept

The structure-activity relationship of a U-type antimicrobial microemulsion system containing glycerol monolaurate and ethanol at a 1∶1 mass ratio as oil phase and Tween 20 as surfactant were investigated along a water dilution line at a ratio of 80∶20 mass% surfactant/oil phase, based on a pseudo-ternary phase diagram. The differential scanning calorimetry results showed that in the region of ...

In the present work specific adsorption phenomena of metal ions at the water –oil interface are studied. Bicontinuous microemulsions were chosen as a model system because of their high specific surface between water and oil phases. Mixing an extremely hydrophobic extractant considered here as the co-surfactant with an extremely hydrophilic sugar surfactant we succeed to formulate microemulsion ...

This paper demonstrates the utility of a noninvasive backscatter fiber optic probe for dynamic light-scattering characterization of a microemulsion comprising sodium dodecyl sulfate/1-butanol/ brine/heptane. The fiber probe, comprising two optical fibers precisely positioned in a stainless steel body, is a miniaturized and efficient self-beating dynamic light-scattering system. Accuracy of part...

This paper is focused on the influence of polystyrene (PS)-poly(1,4-butadiene) (PB)-poly(ethylene oxide) (PEO) triblock terpolymers on the w/o microemulsion of the pseudo-ternary system water/sodium dodecylsulfate (SDS)/xylene-pentanol. Despite the insolubility of the copolymer in water as well as in the xylene-pentanol mixture, it can be incorporated into the w/o microemulsion and interactions...

The absolute bioavailability of famotidine after oral administration is about 40-45% and absorbance only in the initial part of small intestine may be due to low intestinal permeability. Hence, an olive oil based microemulsion formulation with Tween-80 as surfactant and PEG-400 as cosurfactant was developed by using water titration method with the aim of enhancing the intestinal permeability as...

Microemulsions are dispersions of water and oil stabilized by one or mixtures of surfactants. The key differentiators from other dispersions are: (i) domain size of the dispersed phase is of the order of 5-100 nm in size (Schulmann et al., 1959); (ii) thermodynamically stable (Zana, 1994), and (iii) optically isotropic (Danielsson and Lindman, 1981). Commonly observed structures are: oil in wat...

The aim of the present study was to prepare and evaluate different formulations of Diclofenac diethylammonium in microemulsion base with a view to enhance its permeability through the skin. Various o/w and w/o microemulsions of Diclofenac diethylammonium were prepared by the spontaneous emulsification methods. Isopropyl myristate was used as oil phase, Polyoxyethylenesorbitan monooleate and Sor...