P revention of cardiovascular disease is an important therapeutic goal in patients with type 2 diabetes melli-tus (1). Although a low dose of aspirin is recommended for this purpose, some patients were resistant to aspirin (2). We previously reported that spontaneous mi-croaggregation of platelets (SMAPs) formed under no stimulation with exoge-nous agonists were frequently observed in type 2 di...

We have examined the redistribution of acetylcholine receptor (AChR) intramembrane particles (IMPs) when AChR clusters of cultured rat myotubes are experimentally disrupted and allowed to reform. In control myotubes, the AChR IMPs are evenly distributed within the AChR domains of cluster membrane. Shortly after addition of azide to disrupt clusters, IMPs become unevenly scattered, with some mic...

To clarify the mechanism underlying a high risk of thrombotic complications in diabetic patients, we investigated the relationship between HSP27 phosphorylation and the platelet activation induced by adenosine diphosphate (ADP) in diabetic patients. Platelet-rich plasma was prepared from the blood of type 2 diabetes mellitus (DM) patients. By measuring the dose response of platelet aggregation ...

Abstract. Sustainable highly productive agriculture in the arid steppe zone of Western Siberia is possible only on basis optimizing water regime soils. The relevance irrigation increasing due to degradation soil cover, geopolitical and resource potential territories fundamental change development strategy Russia. Light soils prevailing Central Northern Kulund, widely used for crop production, a...

Centroids are key components in many data analysis algorithms such as clustering or microaggregation. They are understood as the central value that minimises the distance to all the objects in a dataset or cluster. Methods for centroid construction are mainly devoted to datasets with numerical and categorical attributes, focusing on the numerical and distributional properties of data. Textual a...

Assembly and mutual proximities of alpha, beta, and gamma(c) subunits of the interleukin 2 receptors (IL-2R) in plasma membranes of Kit 225 K6 T lymphoma cells were investigated by fluorescence resonance energy transfer (FRET) using fluorescein isothiocyanate- and Cy3-conjugated monoclonal antibodies (mAbs) that were directed against the IL-2R alpha, IL-2R beta, and gamma(c) subunits of IL-2R. ...

Understanding the processes underlying carbon (C) stability in soils is of utmost importance context climate change. In this setting, biochar often studied for its persistence and reported to have positive impacts on soil fertility. Whilst recent research has mostly focused short-term effects amendments soil, a better understanding long-term needed. Our study focuses agricultural enriched charc...

This paper shows that it is possible to create metrics for which re-identification is straightforward for situations in which continuous variables have been micro-aggregated one at a time using conventional methods. Introduction The purpose of this document is to provide overall justification on how micro-aggregation generally can yield public-use files in which re-identification rates are extr...

Black C is an essential component of the terrestrial C pool and its formation is often credited as a CO(2) sink by transferring the fast-cycling C from the atmosphere-biosphere system into slower cycling C in the geosphere. This study is the first multi-element K- (C, N, Ca, Fe, Al and Si) soft-X-ray STXM-NEXAFS investigation conducted at a submicron-scale spatial resolution specifically target...

Tonic and clonic muscle spasm of the lower extremities and trunk is a well-known complication of myelography [1, 2] and accidental subdural injection of contrast material [3]. Occasionally , myoclonus also appears after aortography. It is postulated that some of the contrast medium reaches the spinal column through intercostal , lumbar, and lumbosacral segmental arteries. The risk is higher in ...