The extent of fusion in facial sutures has implications for topics ranging from biomechanics to phylogeny reconstruction. An unfortunate limitation of studying sutural fusion in skeletal specimens is that it is difficult to assess whether apparently patent sutures are in fact fused internally. Both histology and microcomputed tomography (CT) are potential tools for solving this, but relatively ...

OBJECTIVE Phantoms with simulating mandibular trabecular bone structure fabricated using micro-stereolithography were applied for a quantitative evaluation of cone-beam computed tomography (CT) images. MATERIALS AND METHODS Phantoms with a three-dimensional lattice, in which a square pillar was set at 0.10, 0.20, 0.30 and 0.40 mm at the edge, spaced at 0.60 mm, were made of an acrylic resin u...

Bone's microporosity plays important biological and mechanical roles. Synchrotron radiation micro-computed tomography (SR CT) is considered the gold standard when evaluating osteocyte lacunae, vascular channels and their three-dimensional (3D) distribution, yet it is a rather exclusive technique. Here, we explored nondestructive desktop micro-computed tomography (desktop CT) as an alternative...

This paper explores new methods to visualize and fuse multi-2D bioluminescence imaging (BLI) data with structural imaging modalities such as micro CT and MR. A geometric, back-projection-based 3D reconstruction for superficial lesions from multi-2D BLI data is presented, enabling a coarse estimate of the 3D source envelopes from the multi-2D BLI data. Also, an intuitive 3D landmark selection is...

This paper aims to evaluate the impact of spectral filtration on image quality in a microcomputed tomography (micro-CT) system. A mouse phantom comprising 11 rods for modeling lung, muscle, adipose, and bones was scanned with 17 s and 2 min, respectively. The current (μA) for each scan was adjusted to achieve identical entrance exposure to the phantom, providing a baseline for image quality eva...

Studies show that the radiation dose received during a micro-CT examination may have adverse effects on living subjects. However, the correlations between the biological effects and the radiation doses have never been thoroughly evaluated in the majority of cases. In this study, we evaluated the biological radiation effects of measured radiation doses in ICR mice using cone-beam micro-CT scans....

Adequate knowledge and accurate characterization of root canal anatomy is an essential prerequisite for successful treatment endodontic surgery. Over the years, ever-increasing body related to human dentition has accumulated. To correct deficiencies in existing systems, a new coding system classifying morphology, accessory canals anomalies been introduced. In recent micro-computed tomography (m...

In this article, we propose to develop the first clinical micro-CT (CMCT) system for human temporal bone imaging in vivo. This CMCT system consists of medical CT and micro-CT scanners either as separate components or in a combination, a cross-modality registration mechanism such as a facial surface scanner, and associated software. This system integrates the strengths of state-of-the-art medica...

PURPOSE Micro-CT is widely used for small animal imaging in preclinical studies of cardiopulmonary disease, but further development is needed to improve spatial resolution, temporal resolution, and material contrast. We present a technique for visualizing the changing distribution of iodine in the cardiac cycle with dual source micro-CT. METHODS The approach entails a retrospectively gated du...