Hydrogels In article number 2213382, Soo-Jin Park, Insik In, Dong-Yeun Koh, Albert S. Lee, and co-workers propose, catechol-functionalized poly(vinyl alcohol)-based hydrogel to inhibit the oxidation of MXene nanofiller while maintaining excellent mechanical electrical properties suitable for strain sensors. Sufficient interaction hydrophobic catechol groups with surface reduces oxidation-access...

Cephalosporins having a catechol through a variety of linkages to the C3 position and a different C7 side chain were prepared. Among them, 3-(catechol-4- ylcarbonyloxy)methylcephalosporin (14) and 3-[(E)-3-(catechol-4-ylcarbonyloxy)-1-propen-1-yl]cephalospo rin (10) showed excellent activity against Gram-negative activity including ceftazidime-resistant Escherichia coli, Pseudomonas aeruginosa,...

A soluble (100,000 x g supernatant) methyltransferase catalyzing the transfer of the methyl group of S-adenosyl-L-methionine to catechols was present in cell extracts of Streptomyces griseus. A simple, general, and rapid catechol-based assay method was devised for enzyme purification and characterization. The enzyme was purified 141-fold by precipitation with ammonium sulfate and successive chr...

The biochemical anti-herbivore defense of trembling aspen (Populus tremuloides Michx.) was investigated in a molecular analysis of polyphenol oxidase (PPO; EC 1.10.3.2). A PPO cDNA was isolated from a trembling aspen wounded leaf cDNA library and its nucleotide sequence determined. Southern analysis indicated the presence of two PPO genes in the trembling aspen genome. Expression of PPO was fou...

Phenolic and polyphenolic compounds are distributed in plant tissues as a secondary metabolite which compromised multiple imperative physiological phenomena. Herein, inhibition mechanism of human carbonic anhydrase isoform II, hCAII, with seven phenolic including phenol, catechol, resorcinol, 4-methyl vanillic acid, trans-cinnamic acid ortho-coumaric has been investigated using quantum mechanic...

H a m i s h G . G r a n t * Department o f Organic Chemistry, University o f Adelaide G . P . O . B o x 498, South Australia 5001 Z. Naturforsch. 34b , 728-733 (1979); received N o v e m b e r 27, 1978 5,6-Disubstituted Indanl -ones , Crotonic Ac id , Po lyphosphor i c Ac id , 1-Methyl Benzofurocyc lopentan-3-one, 1 3C N M R The reaction of several 1,2-disubstituted benzenes with crotonic acid ...

Cell extracts were prepared from Trichosporon cutaneum grown with phenol or p-cresol, and activities were assayed for enzymes catalyzing conversion of these two carbon sources into 3-ketoadipate (beta-ketoadipate) and 3-keto-4-methyladipate, respectively. When activities of each enzyme were expressed as a ratio, the rate for methyl-substituted substrate being divided by that for the unsubstitut...

The metabolic fate of the tyrosine hydroxylase inhibitor, alpha-methyl-para-tyrosine (alpha-MPT), was studied after oral administration of single and multiple doses to patients with pheochromocytoma and essential hypertension. No major urinary excretion product was found other than the drug itself, which accounted for 44-88% of the fate of single or repeated oral doses. Though less than 1% of t...

This study evaluated the biodegradation of catechol by a yeast strain of Candida parapsilopsis in standard medium in Erlenmeyer flasks. Results shown that the highest concentration of catechol caused the longer lag period, demonstrating that acclimatized cultures could completely degrade an initial catechol concentration of 910 mg/L within 48 h. Haldane’s model validated the experimental data a...

To better understand the association of contaminant uranium with natural organic matter (NOM) and the fate of uranium in ground water, spectroscopic studies of uranium complexation with catechol were conducted. Catechol provides a model for ubiquitous functional groups present in NOM. Liquid samples were analyzed using Raman, FTIR, and UV-Vis spectroscopy. Catechol was found to polymerize in pr...