نتایج جستجو برای: methoxy psoralen
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Chem. Abstr. Serv. Reg. No.: 298-81-7 Chem. Abstr. Name: 9-Methoxy-7Hfuro[3,2-g][1]benzopyran-7-one IUPAC Systematic Name: 9-Methoxyfuro[3,2-g]chromen-7-one Synonyms: 5-Benzofuranacrylic acid, 6-hydroxy-7-methoxy-, δ-lactone; Meladinine; 8-methoxy-6,7-furanocoumarin; 8-methoxypsoralen; 8-methoxy[furano3′,2′:6,7-coumarin]; 8-MOP; 8-MP; Oxsoralen; Puvasoralen; Uvadex Description: Silky needles or...
In the presence of S-adenosylmethionine, 2-oxoglutarate, Fe2+ and a reducing agent, cell-free extracts of Streptomyces clavuligerus convert cephalosporin C and 0carbamoyldeacetylcephalosporin C into 7a-methoxy derivatives. No synthesis of a 7a-methoxy derivative of deacetylcephalosporin C was detected in the system used, and the 7a-methoxy derivative of deacetoxycephalosporin C was produced onl...
Chem. Abstr. Serv. Reg. No.: 298-81-7 Chem. Abstr. Name: 9-Methoxy-7Hfuro[3,2-g][1]benzopyran-7-one IUPAC Systematic Name: 9-Methoxyfuro[3,2-g]chromen-7-one Synonyms: 5-Benzofuranacrylic acid, 6-hydroxy-7-methoxy-, δ-lactone; Meladinine; 8-methoxy-6,7-furanocoumarin; 8-methoxypsoralen; 8-methoxy[furano3′,2′:6,7-coumarin]; 8-MOP; 8-MP; Oxsoralen; Puvasoralen; Uvadex Description: Silky needles or...
A series of naphthopyran derivatives 3a-f were prepared. Reaction of 2-amino-4-(p-chlorophenyl)-7-methoxy-4H-naphtho[2,1-b]pyran-3-carbonitrile (3b) with Ac2O afforded two products, 2-acetylamino-7-methoxy-4-(p-chlorophenyl)-4H-naphtho-[2,1-b]pyran-3-carbonitrile (4) and 10,11-dihydro-3-methoxy-9-methyl-12-(p-chloro-phenyl)-12H-naphtho[2,1-b]pyran[2,3-d]pyrimidine-11-one (5) and treatment of 3b...
In the mol-ecule of the title compound, C(18)H(19)N(3)O(3), the triazole ring is oriented with respect to the 3-methoxy-phenyl and 2-methoxy-phenyl rings at dihedral angles of 11.79 (3) and 89.22 (3)°, respectively. The dihedral angle between the two benzene rings is 85.95 (3)°. In the crystal structure, inter-molecular O-H⋯N and C-H⋯O hydrogen bonds link the mol-ecules. There is a π-π contact ...
BACKGROUND AND OBJECTIVE Extracorporeal photochemotherapy (ECP) is a therapeutic approach based on the biological effects of ultraviolet light (UV) - A and psoralens on mononuclear cells collected by apheresis. Recently, ECP has been under investigation as an alternative treatment for various immune and autoimmune diseases. The aim of this study was to evaluate the safety and feasibility of a n...
New approaches using biotinylated-psoralen as a probe for investigating DNA structure have revealed new insights into the relationship between DNA supercoiling, transcription and chromatin compaction. We explore a hypothesis that divergent RNA transcription generates negative supercoiling at promoters facilitating initiation complex formation and subsequent promoter clearance.
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