conclusions it seems matrix group interventions increase the effectiveness of methadone treatment by reducing the relapse prevention, the dose of methadone and remaining in treatment. results results showed that the effect of matrix group interventions on reducing relapse (p < 0.05), increasing the maintenance of treatment (p < 0.01), increasing the treatment compliance, reducing anger, anxiety...

BACKGROUND The expansion of methadone maintenance treatment in mountainous areas in still limited and little is known about its health impacts on drug users. This study aimed to examine health-related quality of life (HRQOL) and health care access among patients engaging in methadone maintenance treatment (MMT) in Tuyen Quang, a mountainous province in Vietnam. METHODS We conducted a cross-se...

OBJECTIVES Our objective was to determine the impact that a patient's geographic status has on the efficacy of first-time methadone maintenance therapy (MMT) retention. METHODS We conducted an observational cohort study using administrative health care databases for patients who commenced methadone therapy between 2003 and 2012. Patients were stratified on the basis of their location of resid...

BACKGROUND Using our research findings, we explore Harm Reduction and Methadone Maintenance Treatment (MMT) using an intersectional lens to provide a more complex understanding of Harm Reduction and MMT, particularly how Harm Reduction and MMT are experienced differently by people dependent on how they are positioned. Using the lens of intersectionality, we refine the notion of Harm Reduction b...

Background: Substance abuse and consequently the use of methadone in Iran are reported at high levels. Drugs alter sexual function by affecting the organs of the body. The aim of this study was to evaluate sexual functioning and serum testosterone levels in opiate addicts, individuals receiving methadone maintenance treatment (MMT), and healthy men living in the city of Rafsanjan, Iran, in 2016...

Brain-derived neurotrophic factor (BDNF) signaling pathways have been shown to be essential for opioid-induced plasticity. We conducted an exploratory study to evaluate BDNF variability in opioid addict responders and nonresponders to methadone maintenance treatment (MMT). We analyzed 21 single nucleotide polymorphisms (SNPs) across the BDNF genomic region. Responders and nonresponders were cla...

BACKGROUND Concomitant cocaine use is a major problem in clinical practice in methadone maintenance treatment (MMT) and may interfere with successful treatment. Data from European methadone populations is sparse. This register-based study sought to explore the association between prescribed methadone dose and concomitant cocaine and heroin use in the methadone population of Basel City. METHOD...

OBJECTIVE There is a significant interindividual variability in treatment outcomes in methadone maintenance treatment (MMT) for opioid use disorder (OUD). This prospective cohort study examines the impact of comorbid psychiatric disorders on continued illicit opioid use in patients receiving MMT for OUD. METHODS Data were collected from 935 patients receiving MMT in outpatient clinics between...

the current preliminary study aimed to explore the reasons that a group of opiate-dependent patients reported for entry into opium tincture treatment (ott).through examinations of 52 qualitative focus group interviews with patients from six ott centers and 10 health providers (in key informant interviews) in tehran, this study highlights the factors that participants reported as the reasons ass...

AIMS To identify dose-tapering strategies associated with sustained success following methadone maintenance treatment (MMT). DESIGN Population-based retrospective cohort study. SETTING Linked administrative medication dispensation data from British Columbia, Canada. PARTICIPANTS From 25 545 completed MMT episodes, 14 602 of which initiated a taper, 4183 individuals (accounting for 4917 MM...