An inspection of the active site region of metallo-enzymes leads to two conclusions. (i) Individual attacking groups usually have uncommon physical properties. (ii) The active site region is cooperatively linked with a large part of the enzyme. Such an interaction is common to heterogeneous catalysts but is absent in homogeneous catalysts. It is concluded that the energetics of catalysis requir...

We consider the approximate solution of integral equations of the form y(t) /if k(t,s)y(s)ds = f(t), where the conditions on k(t,s) are such that kernels of the Wiener-Hopf form k(t, s) = n(t s) are included in the analysis. The finite-section approximation, in which the infinite integral is replaced by }§ for some ß > 0, yields an approximate solution _Vß(t) that is known, under very general c...

BACKGROUND Well baby visits (WBVs) are a cornerstone of early childhood health, but few studies have examined the correlates of WBVs for socioeconomically vulnerable infants. The study objective was to identify factors related to the number of WBVs received by Medicaid-enrolled infants in the first three years of life and to present a preliminary explanatory model. METHODS We analyzed Iowa Me...

Lesions of focal segmental glomerulosclerosis (FSGS) are a pathological hallmark of progressive glomerular injury. Glomerulosclerosis frequently complicates most renal diseases, and is characterized by the collapse of the glomerular tuft with the accumulation of mesangial matrix. Transforming growth factor-ß (TGF-ß) is a key regulator of extracellular matrix (ECM) protein synthesis in renal cel...

BACKGROUND Previous studies suggested that pre-operative comorbidity was a risk factor for worse outcomes after TKA. To our knowledge, studies have not examined whether postoperative changes in comorbidity impact pain and function outcomes longitudinally. Our objective was to examine if increasing comorbidity postoperatively is associated with worsening physical function and pain after primary ...

Z. Naturforsch. 50c, 345-352 (1995); received January 27/February 20, 1995 Liverworts, Frullania, Flavone Aglycones, Acylated Flavone Glycosides, Chemotaxonomy From Frullania teneriffae 5 known flavone aglycones and 6 flavone glycosides were iso­ lated, among them the new 6-OH-luteolin-6-0-ß-D-glucoside-7-0-ß-D-glueoside-6'"-(3-hydroxy-3-methylglutaroylester). F. cesatiana contains 2 flavone-di...

Metallo-beta-lactamase production is an important mechanism for carbapenem resistance of Pseudomonas aeruginosa , which represents an emerging public health challenge. We report the case of a patient admitted to an intensive care unit, with sepsis caused by multidrug-resistant São Paulo Metallo-beta-lactamase-1-producing P. aeruginosa . This is the first case of infection by this pathogenic str...

Self-assembly of 2,4,6-tripyridyl-1,3,5-triazine (tpt) subunits with arene ruthenium building blocks and oxalato bridges affords cationic triangular metallo-prisms of the type [Ru6(arene)6(tpt)2(C2O4)3]6+ (arene = C6Me6 and p-Pr(i)C6H4Me); the unexpected double helical chirality of the metallo-prisms observed in the solid state persists in solution giving rise to two different stereodynamic pro...

BACKGROUND Over half of kidney cancer survivors (KCS) are completely inactive and only a quarter are meeting physical activity (PA) guidelines. This highlights the need to identify and understand the determinants of PA in this understudied population. The purpose of this study is to determine the social cognitive correlates of PA intention and behavior in KCS using the Theory of Planned Behavio...

conclusions our findings showed a high occurrence of metallo-β-lactamase production among p. aeruginosa isolates in burn patient infections in our region. also, there are p. aeruginosa isolates carrying the bla-vim-1 and bla-vim-2 genes in isfahan province. background metallo-β-lactamase-production among gram-negative bacteria, including pseudomonas aeruginosa, has become a challenge for treatm...