BACKGROUND The purpose of this study was to characterize cardiovascular risk factors in a rural pediatric population by body mass index (BMI) category and the presence of the metabolic syndrome. METHODS Data on 13,018 children and adolescents (aged younger than 20 years) from West Virginia and Ohio in 2005-2006 were obtained from the C8 Health Project to determine the prevalence of overweight...

Much evidence supports a pivotal role for inflammation in atherosclerosis. C-reactive protein (CRP), the prototypic marker of inflammation in humans, is a cardiovascular risk marker and may also promote atherogenesis. CRP levels are increased in metabolic syndrome and hypertension and confer increased risk of cardiovascular events in patients in these subgroups. Statins have been shown to lower...

INTRODUCTION To review the definitions of the metabolic syndrome according to various expert groups and assess their relevance to clinical practice. MATERIALS AND METHODS Medline searches were conducted to identify studies which addressed: (i) the utility of the metabolic syndrome compared to multivariable predictive functions for the identification of individuals at high risk of type 2 diabe...

conclusions no association was found between tfam promoter methylation and mes. the present study suggests that the tfam promoter methylation is not associated with risk of mes. objectives the aim of study was to investigate the possible association between promoter methylation of mitochondrial transcription factor a (tfam) and mes. patients and methods dna was extracted from peripheral blood o...

AIM Hyperhomocysteinaemia and the metabolic syndrome are associated with increased cardiovascular risk. We investigated whether there is a link between the metabolic syndrome or its components and homocysteine levels in a population without cardiovascular disease. METHODS From the population sample of 382 participants (286 females and 96 males) we isolated those reflecting the metabolic syndr...

objectives the aim of this study was to evaluate the effect of cranberry extract on some components of metabolic syndrome. patients and methods in a randomized, double-blind placebo-controlled clinical trial, 48 obese and overweight females diagnosed with ms were assigned into two groups to receive cranberry supplement or placebo for an eight-week period. serum glucose, lipoproteins, inflammato...

OBJECTIVE With increasing evidence about the cardiovascular risk associated with postprandial nonfasting glucose and lipid dysmetabolism, it remains uncertain whether the postprandial glucose concentration increases the ability of metabolic syndrome to predict cardiovascular events. RESEARCH DESIGN AND METHODS This was an observational study of 15,145 individuals aged 35-75 years without diab...

Objectives: Obstructive sleep apnoea (OSA) is a condition wherein collapse of the upper airway during results in decreased or complete cessation airflow. The association OSA with increased cardiovascular morbidity, mortality, and various risk factors known for long time. Metabolic syndrome cluster metabolic abnormalities, insulin resistance as central pathophysiological feature ‘Syndrome X’ Z’....