The meniscus plays important roles in proper knee function. It was recently reported that meniscus degeneration was associated with progression of osteoarthritis (OA). However, little is known about the effects of degradative enzymes on the meniscus matrix, primarily collagen type I and aggrecan, during OA. This study examined the effects of metalloproteinase (MMP) and aggrecanase on the destru...

BACKGROUND Discoid lateral meniscus is common in children. Arthroscopic partial resection is indicated in symptomatic cases generally achieving satisfactory results. CASE PRESENTATION We present a case of an incomplete discoid lateral meniscus of the right knee in an 11 year-old boy, treated with arthroscopic partial resection, which developed a re-growth of the remnant, restoring the pre-ope...

OBJECTIVE To identify an appropriate cell source for the generation of meniscus substitutes, among those which would be available by arthroscopy of injured knee joints. METHODS Human inner meniscus cells, fat pad cells (FPC), synovial membrane cells (SMC) and articular chondrocytes (AC) were expanded with or without specific growth factors (Transforming growth factor-beta1, Fibroblast growth ...

Effect of the capillary meniscus on the instability of large Prandtl number Czochralski melt flow is studied experimentally. The measurements are conducted in two experimental facilities by two independent non-intrusive optical techniques. The quantitative results are presented as dependencies of the critical Grashof number (critical temperature difference) on the meniscus height for different ...

We report a case of double-layered lateral meniscus, where an accessory proximal hemimeniscus was overlying the body and posterior horn of the lateral meniscus. It lay 1-2 mm proximal and parallel to the normal lateral meniscus with its periphery attached to the capsule and was significantly thinner and more mobile than its underlying counterpart. The accessory hemimeniscus was resected arthros...

OBJECTIVE To verify the biologic links between progressive cellular and structural alterations within knee joint components and development of symptomatic chronic pain that are characteristic of osteoarthritis (OA), and to investigate the molecular basis of alterations in nociceptive pathways caused by OA-induced pain. METHODS An animal model of knee joint OA pain was generated by intraarticu...

INTRODUCTION The proximity of the posterior horn of the lateral meniscus to the popliteal artery determines a risk of vascular injury in its suture. The aim of this study is to determine the location of the popliteal artery, and to establish the minimal distance from the posterior wall of the lateral meniscus to the artery, the common peroneal nerve (CPN), and its correlation to other variables...

The aims of a meniscal replacement are: 1) to reduce the pain experienced by some patients following meniscus resection; 2) to prevent the degenerative changes of cartilage and the changes in subchondral bone following meniscus resection; 3) to avoid or reduce the risk of osteoarthritis following meniscus resection; 4) to restore optimally the mechanical properties of the knee joint after menis...

This prospective double-blind study was designed to evaluate the capability of magnetic resonance imaging to serve as a diagnostic tool in patients who have a clinically suspected disorder of the meniscus. The imaging studies provided a diagnostic accuracy of 72 per cent, a sensitivity of 88 per cent, and a specificity of 57 per cent. The positive and negative predictive values were 66 and 83 p...

This study aimed to verify the accuracy of low-field-intensity magnetic resonance imaging (MRI) in diagnosing meniscus tears. A total of 171 patients were examined through low-field-intensity MRI to detect meniscus injuries. These patients were then diagnosed through arthroscopy. Examination results were recorded and compared. The accuracy of the diagnosis for internal and external meniscus tea...