Experimental evidence has linked increased arousal to enhanced memory retention. There is also evidence that procedures reducing arousal, i.e., mental relaxation, might improve memory, but conflicting results have been reported. To clarify this issue, we studied the effects of a single session of relaxation training on incidental visual long-term memory. Thirty-two relaxation-naive subjects vie...

bile duct ligation (bdl) is shown to induce cholestasis-related liver function impairments as well as consequent cognitive dysfunctions (i.e. impaired learning and memory formation). this study investigates the effects of cholestasis (14, 21 and 28 days post bile duct ligation) on spatial and non-spatial novelty detection, using a non-associative task. male mice weighing 30-35 g were used. chol...

Introduction: Alzheimer’s disease (AD) is a enfeeble neurodegenerative disorder characterized by increased β-amyloid (Aβ) deposition and neuronal dysfunction leading to impaired learning and recall. Among proposed risk factors, impaired cholinergic transmission is a main cause for incidence of disease. Methods: In the present study, effects of the intracerebroventricularly administration of an ...

There is growing interest in flavonoids for their wide array of biological actions. In neurodegenerative disorders these naturally occurring polyphenolic compounds, are known to inhibit proinflammatory mediators such as in TNF–? and IL-6 in lipopolysaccharide (LPS) stimulated neuronal degeneration, which are associated with Alzheimer’s and Parkinson’s disease. Recent studies on flavonoids have ...

The present study investigated the effect of buspirone on memory formation in an aversive learning task. Male Wistar rats were trained on the inhibitory avoidance task and tested for retention 1 day after training. They received peripheral or intra-amygdala administration of buspirone or other 5-HT1A drugs either before or after training. Results indicated that pretraining systemic injections o...

AIMS In the present study, the effects of bilateral intra-dorsal hippocampal (intra-CA1) injections of cholinergic agents on muscimol state-dependent memory were examined in mice. MAIN METHODS A single-trial step-down passive avoidance task was used for the assessment of memory retention in adult male NMRI mice. KEY FINDINGS Pre-training intra-CA1 administration of a GABA-A receptor agonist...

Memory and learning are considered as the most complicated and important processes of behavioral sciences. On the other hand, considering the wide .and progressively increasing applications of anesthetic agents all over the world, it is of great importance to have a reasonable knowledge regarding their effects on the memory process and its retrieval. The main purpose of this study was to evalua...

Two groups of Clark’s nutcrackers (Nucifraga columbiana) were trained to use either a stay or shift response strategy in a radial maze analogue. Each trial had a preretention stage, a retention interval, and a postretention test. In Experiment 1, acquisition with a 5-min retention interval was studied. Response strategy did not affect the rate at which the task was learned. Performance followin...

Two groups of Clark's nutcrackers (Nucifraga columbiana) were trained to use either a stay or shift response strategy in a radial maze analogue. Each trial had a preretention stage, a retention interval, and a postretention test. In Experiment 1, acquisition with a 5-min retention interval was studied. Response strategy did not affect the rate at which the task was learned. Performance followin...