Traumatic brain injury (TBI) patients have working memory deficits and altered patterns of brain activation during this function. The evolution of the impairment has not been examined to date. This study investigated longitudinal changes in brain activation during a working memory task. Twelve patients with severe and diffuse TBI and ten healthy matched controls were fMRI scanned twice at a 6-m...

The latest neuroimaging studies about implicit memory (IM) have revealed that different IM types may be processed by different parts of the brain. However, studies have rarely examined what subtypes of IM processes are affected in patients with various brain injuries. Twenty patients with frontal lobe injury, 25 patients with occipital lobe injury, and 29 healthy controls (HC) were recruited fo...

Children born preterm and of very low birth weight are at increased risk of learning difficulties and educational under-achievement. However, little is known about the specific neuropsychological problems facing these children or their neurological basis. Using prospective longitudinal data from a regional cohort of 92 preterm and 103 full-term children, this study examined relations between te...

The aim of this research is to evaluate whether posttraining systemic epinephrine is able to improve object recognition memory in rats with memory deficits produced by traumatic brain injury. Forty-nine two-month-old naïve male Wistar rats were submitted to surgical procedures to induce traumatic brain injury (TBI) or were sham-operated. Rats were trained in an object recognition task and, imme...

Abstract Erythropoietin (EPO) improves neuronal mitochondrial function and cognition in adults after brain injury those afflicted by psychiatric disorders. However, the influence of EPO on mitochondria during development remains unexplored. We previously observed that stimulates hippocampal-specific maturation synaptogenesis early postnatal mice. Here we show promotes respiration developing hip...

‘Severe’ Traumatic Brain Injury (TBI) survivors are likely to be hospitalised and experience Post Amnesia (PTA): a transient state of confusion, disorientation memory loss, until the return continuous memory. Survivors often distressing ‘islands’ during PTA, this can exacerbate psychological deterioration lead additional poor outcomes if left untreated. The literature for neuropsychological reh...

BACKGROUND AND PURPOSE Memory impairment can be progressive in neurodegenerative diseases, and physiological ageing or brain injury, mitochondrial dysfunction and oxidative stress are critical components of these issues. An early clinical study has demonstrated cognitive improvement during erythropoietin treatment in patients with chronic renal failure. As erythropoietin cannot freely cross the...

Memory impairments are one of the most common consequences of acquired brain injury. Poor memory can have a severe impact on a person’s daily functioning and his/her quality of life. While research provides some support for using external, compensatory strategies (e.g. diaries, lists, visual or electronic reminders), empirical evidence in favor of internal, restorative strategies (i.e. learning...

Citation: Foster PP (2015) Mild traumatic brain injury and delayed alteration of memory processing. A commentary on History of mild traumatic brain injury is associated with deficits in relational memory, reduced hippocampal volume, and less neural activity later in life A brain traumatism may result from focal impact upon the head and/or sudden acceleration/deceleration kinetic forces applied ...

This study examined the neurobehavioural effects of closed head injury (CHI) in adults aged 50 years and older. Twenty two mild to moderate CHI patients who were within seven months of the injury were administered measures of language, memory, attention, and executive functioning. Compared with demographically similar normal controls, the patients exhibited significantly poorer functioning on t...