visceral leishmaniasis is the second most common cause of fever of unknown origin in our study. this disease is not common in adults, although it's endemic among the pediatric age group. the majority of the affected individuals were young. high grade spiking fever, chills and splenomegaly were unique findings. other common findings were neutropenia, anemia, abnormal liver function tests, s...

Cutaneous leishmaniasis (CL) has been recognized as a major public health problem in several countries. It is highly endemic in the north and east Mediterranean regions in the Syrian Arab Republic with more than 75.9% of all CL cases recorded from these regions. Pentavalent antimonials have been considered as standard treatment for leishmaniasis. Use of pentavalent antimonials to treat leishman...

Although intralesional meglumine antimoniate (MA) infiltration is considered an option for cutaneous leishmaniasis (CL) therapy and is widely used in the Old World, there have been few studies supporting this therapeutic approach in the Americas. This study aims to describe outcomes and adverse events associated with intralesional therapy for CL. This retrospective study reviewed the experience...

Background: Several treatment modalities have been used for cutaneous leishmaniasis (CL) with various results. In vitro and in vivo studies have shown inhibitory effects of zinc sulfate (ZnSO4) on Leishmania parasites. Objective: To compare the efficacy of intralesional injections of 2% ZnSO4 solution with meglumine antimonate (Glucantime) in the treatment of acute Old World CL. Patients ...