Background and Purpose Activation of the defence reaction inhibits baroreflex response via intermediate rostro-ventromedial medulla (B3 raphé) nucleus tractus solitarius (NTS). Our aim was to determine whether how inhibition, induced by disinhibition rostral cuneiform (part pathway), involves 5-HT neurons in B3 5-HT3 receptors NTS. Experimental Approach We performed immunohistochemistry anatomi...

we report an unusual case of a young male with cerebellar hemangioblastoma treated previously for medullary carcinoma of thyroid, whose pet/ct scans revealed a constellation of findings that suggested the rare von hippel lindau syndrome. the diagnosis was clinched by confirming the findings on whole body contrast enhanced computed tomography (cect) and contrast enhanced magnetic resonance imagi...

the coexistence of medullary thyroid carcinoma (mtc), papillary thyroid carcinoma (ptc) and parathyroid adenoma is an uncommon clinical entity. here, we report a case of mtc, ptc, and parathyroid adenoma diagnosed incidentally on a routine physical examination of the neck for the work-up of diabetes. the patient had neither symptoms of hypercalcemia nor those related to mtc and ptc.

medullary thyroid carcinoma (mtc) occurs in both sporadic (75%) and hereditary (25%) forms. the missense mutations of the rearranged during transfection (ret) proto-oncogene in mtc development have been well demonstrated. the aim of this study was to investigate frequency of g691s/s904s haplotype in mtc patients and their relatives.in this research 293 participants were studied, including 181 p...

Hepatocyte nuclear factor 1β (HNF1β) is an essential transcription in development of the kidney, liver, and pancreas. HNF1β-mediated target genes dependent on cell type stage. Nevertheless, regulation HNF1β function by enhancers co-factors that allow this cell-specific largely unknown. To map interactome we performed mass spectrometry a mouse kidney inner medullary collecting duct line. Pterin-...

BACKGROUND AND PURPOSE The demonstration of prominent medullary veins in the deep white matter ipsilateral to acute ischemic stroke has been shown to predict poor clinical outcome. We have investigated the prognostic implications of prominent medullary veins in patients with subacute stroke who present outside the therapeutic window for revascularization therapy. MATERIALS AND METHODS Forty-t...

Key points Dysfunctions in the hypoglossal control of tongue extrinsic muscles are implicated obstructive sleep apnoea (OSA) syndrome. Chronic intermittent hypoxia (CIH), an important feature OSA syndrome, produces deleterious effects on motor oropharyngeal resistance, but whether motoneurones innervating affected by CIH is unknown. We show that enhanced respiratory‐related activity rat nerve p...

Parathyroid carcinoma is the rarest endocrine cancer with aggressive behaviour. It may be presented as a feature of severe hypercalcemia, musculoskeletal involvement and neck mass. There should high clinical suspicion if there marked very parathyroid hormone levels, palpable mass, recurrent laryngeal nerve palsy due to invasion bone renal symptoms. Thyroid pathology has been seen in 15-70% pati...

The present study was undertaken to identify trigeminal premotor interneurons that become activated during carbachol-induced active sleep (c-AS). Their identification is a critical step in determining the neural circuits responsible for the atonia of active sleep. Accordingly, the retrograde tracer cholera toxin subunit B (CTb) was injected into the trigeminal motor nuclei complex to label trig...